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Biomedical subjects

D J Aloysius

Publications and source records attributed to D J Aloysius.

At least 19 recordsLinked to original sources
PubMed1997

Wijerama House.

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History, 19th Century↗
PubMed1996

Home accidents in Sri Lanka--multicentre study.

OBJECTIVE: To determine the pattern of home accidents treated in four types of clinical practice. SETTING: A general practice and four hospital-based practices in accident service, general surgery and paediatric surgery. MATERIALS: Data were collected on a pre-tested questionnaire from 2672 patients who comprised all the home accident patients treated at the 5 centres during a 12 month period. RESULTS: Questionnaire was analysed and results presented in regard to several variables including age, size of household and peak period, location and type of accident. CONCLUSION: The characteristics of the victim, agent, environment, circumstances, cause and time of accident as determined by this study may be useful to formulate a prevention program.

Accidents, Home↗
PubMed1988

Paralysis, rhabdomyolysis and haemolysis caused by bites of Russell's viper (Vipera russelli pulchella) in Sri Lanka: failure of Indian (Haffkine) antivenom.

In Sri Lanka, Russell's viper, Vipera russelli pulchella, kills more people than any other species of snake. At Anuradhapura in the dry central zone of the island we studied 23 patients with systemic envenoming after proven bites. Seventy-three per cent had swelling at the bite site. Neurotoxicity was the commonest sign of systemic envenoming: 82 per cent had external ophthalmoplegia and 77 per cent had ptosis. Incoagulable blood was found in 59 per cent but only 36 per cent had spontaneous bleeding. Other signs included generalized muscle tenderness (32 per cent), black urine (27 per cent) and persistent oliguria (9 per cent). Laboratory studies showed evidence of a severe clotting disorder: fibrinogen was often depleted as were factors V and X. Fibrin degradation products, including cross-linked moieties, were grossly elevated, clear evidence for enhanced fibrinolysis. Intravascular haemolysis, unrelated to G6PD deficiency, was often present. Myoglobin was detected in the plasma of all 19 patients tested (range 100- greater than 8000 ng/ml) and in the urine in 14 of 18 patients (110- greater than 16,000 ng/ml). Venom antigen (16.5-702 ng/ml) was detected by specific ELISA in the serum of all patients. Its concentration fell with the administration of 50-200 ml of Haffkine polyspecific antivenom raised against Indian venoms. Complete permanent clearance of venom antigen from the circulation was seen in only one of 21 patients who were followed until discharge. Blood coagulability was restored between one and 25 h (mean 8.8) after the first dose of antivenom in the 12 surviving patients whose clotting defect could be followed; no dramatic reversal of neuromyotoxic signs was seen. Haffkine antivenom thus has limited efficacy against systemic poisoning by Russell's viper in Sri Lanka.

Adolescent↗
PubMed1983

Histamine poisoning on ingestion of tuna fish.

When tuberculosis patients on isoniazid eat certain varieties of fish they may develop a histamine reaction. The occurrence of this reaction in a mother and daughter on ingestion of tuna fish is reported. Two other members of the family who were on treatment for tuberculosis but had not taken isoniazid on the day of the episode were unaffected by the same meal.

Adult↗
PubMed1982

Family medicine.

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Drug Prescriptions↗