FDA poison control notes. Citations from the recent literature.
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Animals↗
Biomedical subjects
D J Brancato
Publications and source records attributed to D J Brancato.
The FDA's poison control case report category summary. Top 10 for calendar years - '79, '80, '81.
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Adolescent↗
Recognizing potential toxicity of phenol.
Data is presented which correlates phenol levels in human urine with inhalatory and skin exposures (phenol is rapidly collected and excreted in urine). "Normal" phenol levels in human urine are compared with urine levels resulting from exposure to phenol. A correlation is made between urine phenol levels and potential human toxicity.
Body Burden↗
Cadmium levels in hair and other tissues during continuous cadmium intake.
Rats that received cadmium 300 ppm in drinking water (average daily cadmium intake = 4.5 mg/rat) for 12 wk attained peak cadmium levels of 112, 34, and 19 mug/g in hair, liver, and kidney, respectively, at week 4. Rats that ingested cadmium 200 ppm (average daily cadmium intake = 3.6 mg/rat) for 13 wk attained peak cadmium levels of 29 mug/g in kidney at week 7, and 94 and 27 mug/g in hair and liver, respectively, at week 9. Despite continuous exposure to the heavy metal, tissue cadmium concentrations declined to steady-state levels of 24-33 mug/g in hair and 10-17 mug/g in liver and kidney. Histopathologic effects were not observed in liver or kidney. In contrast to cadmium in hair, blood cadmium levels, which remained consistently low (less than 0.04 mug/ml) throughout the study, did not correlate with changes in cadmium levels in liver and kidney.
Animals↗