Biomedical subjects

D J Cochrane

Publications and source records attributed to D J Cochrane.

9 recordsLinked to original sources

PubMed2005

Acute whole body vibration training increases vertical jump and flexibility performance in elite female field hockey players.

OBJECTIVE: To quantify the acute effect of whole body vibration (WBV) training on arm countermovement vertical jump (ACMVJ), grip strength, and flexibility performance. METHODS: Eighteen female elite field hockey players each completed three interventions of WBV, control, and cycling in a balanced random manner. WBV was performed on a Galileo machine (26 Hz) with six different exercises being performed. For the control, the same six exercises were performed at 0 Hz, whilst cycling was performed at 50 W. Each intervention was 5 min in duration with ACMVJ, grip strength, and flexibility measurements being conducted pre and post intervention. RESULTS: There was a positive interaction effect (intervention x pre-post) of enhanced ACMVJ (p<0.001) and flexibility (p<0.05) parameters following WBV; however no changes were observed after the control and cycling interventions. There was no interaction effect for grip strength following the three interventions. CONCLUSIONS: Acute WBV causes neural potentiation of the stretch reflex loop as shown by the improved ACMVJ and flexibility performance. Additionally, muscle groups less proportionally exposed to vibration do not exhibit physiological changes that potentiate muscular performance.

Adolescent↗

PubMed2005

The assessment of an intermittent high intensity running test.

AIM: In multiple sprint sports the ability to perform repeated short duration bouts of maximal intensity exercise appears to be sport specific than the ability to perform prolonged continuous exercise or produce a single bout of exercise. However, previous studies have not verified a field test method with an appropriate intermittent anaerobic exercise pattern. The purpose of this study was to establish the reliability and validity of the Intermittent Anaerobic Running Test (IAnRT) primarily developed for soccer players. METHODS: Twenty-nine trained male adolescent soccer players performed two separate 20 m sprints and the IAnRT on an indoor running track in each of two testing sessions separated by one recovery day. The IAnRT consisted of 10 20-m sprints with 20-s recovery periods between the sprints. RESULTS: The mean running speed (Vm) and the speed at the beginning and the end of the IAnRT (V1+2, V9+10) confirmed good reliability. The relative mean speed index was the preferred indicator for assessing the ability to maintain short duration running performance during the intermittent exercise mode. Using confirmatory factor analysis the running performance of IAnRT was best explained by one general factor and one subfactor which consequently joined the general one from the 6th sprint (P=0.03, Bentler's d=0.99, RMSR=0.03). CONCLUSION: The IAnRT provided reliable and valid performance indices, which reflect the maximal anaerobic running power and capacity for repeated running sprints.

Adolescent↗

PubMed1999

Do changing patterns of heat and humidity influence thermoregulation and endurance performance?

The purpose of this project was to determine whether changing patterns of temperature and humidity, as expected in the morning versus afternoon, had a differential effect on thermoregulation and endurance performance. Eight male distance runners each participated in two heat pattern tests consisting of two hours treadmill running at 70%-maximum oxygen consumption. The mean heat load for each test was identical (22.2 degrees C wet bulb temperature) but either dry bulb temperature increased (24 to 27.5 degrees C) or decreased (27.5 to 24 degrees C) over the course of the two hour heat stress test. Whole body sweat rate was 10.7% higher (p<0.05) and there was greater plasma volume loss (2.7 versus 1.6%, p<0.05) in the cooling versus warming pattern test. Mean skin and body temperature changed in a significantly different (p<0.05) manner between the two patterns and closely followed ambient dry bulb temperature change. The thermoregulatory variables of heart rate and rectal temperature were not affected and performance did not differ between pattern tests. Ratings of perceived exertion (RPE) and oxygen consumption were also not significantly different between cooling and warming test. In summary, although some minor differences were noted, thermal homeostasis was maintained equally well during either warming or cooling for wet bulb temperatures between 24 and 27 degrees C. The mean heat load is therefore more important than changing patterns of temperature and humidity in determining an individual's physiological response to exercise in a warm environment.

Adult↗

PubMed1997

Ventricular pacing with a novel gastroesophageal electrode: a comparison with external pacing.

Temporary endocardial pacing is a technically demanding invasive procedure requiring sterile precautions and access to fluoroscopy. External (transcutaneous) pacing requires high current for capture and is poorly tolerated in the conscious patient. An esothoracic pacing system has been developed capable of reliable ventricular capture. The flexible gastroesophageal electrode is passed into the stomach. The distal 6 cm is angled to 90 degrees with an internal pulley system, positioning the tip of the gastroesophageal electrode in the fundus of the stomach. Ventricular pacing is performed with a spherical electrode (cathode) mounted on the gastroesophageal electrode tip in conjunction with a chest pad (anode) positioned medial to the cardiac apex. Of 91 subjects in which esothoracic pacing was attempted, 86 (94.5%) demonstrated successful ventricular capture at the maximum pulse duration used (40 msec). Threshold current for ventricular capture ranged from 22.5 +/- 8.1 mA at a pulse duration of 40 msec to 29.9 +/- 8.6 mA at a pulse duration of 10 msec. Esothoracic pacing was compared with external pacing in a subgroup (n = 30) of patients. Ventricular capture with the gastroesophageal electrode was more common when compared with the external approach (27 [90%] of 30 vs 13 [43.3%] of 30, p < 0.001). In those subjects in whom ventricular capture was obtained with both methods, threshold current for capture was significantly lower with the esothoracic approach. This gastroesophageal electrode may be useful in the emergency management of acute bradyarrhythmias.

Adult↗

PubMed1997

A gastroesophageal electrode for atrial and ventricular pacing.

Temporary transvenous cardiac pacing requires technical expertise and access to fluoroscopy. We have developed a gastroesophageal electrode capable of atrial and ventricular pacing. The flexible polythene gastroesophageal electrode is passed into the stomach under light sedation. Five ring electrodes, now positioned in the lower esophagus, are used for atrial pacing. A point source (cathode) on the distal tip of the electrode, now positioned in the gastric fundus, is used for ventricular pacing. Two configurations of atrial and ventricular pacing were compared: unipolar and bipolar. During unipolar ventricular pacing the indifferent electrode (anode) was a high impedance chest pad. For bipolar ventricular pacing the indifferent electrode was a ring electrodes placed 2 cm proximal to the tip. Unipolar atrial pacing was performed with 1 of 5 proximal ring electrodes acting as cathode ("cathodic") or as anode ("anodic") in conjunction with a chest pad. Bipolar atrial pacing was performed using combinations of 2 of 5 ring electrodes. Atrial capture was obtained in all 55 subjects attempted. When all electrode combinations were compared, atrial capture was significantly more frequent using the bipolar approach (153/210 bipolar, 65/210 unipolar; t = 7.37, P < 0.001). For unipolar atrial pacing, cathodic stimulation (from esophagus) was more successful than anodic stimulation (cathodic 62/105, anodic 20/105; t = 5.81, P < 0.001). In 43 subjects attempted unipolar ventricular pacing resulted in a higher frequency of capture than the bipolar approach (unipolar 41/43 (95.3%), bipolar 19/43 (44.2%); P < 0.001). In conclusion, atrial pacing was optimal using pairs of ring electrodes ("bipolar") while ventricular pacing was optimal using the distal electrode tip (cathode) in conjunction with a chest pad electrode ("unipolar"). This gastroesophageal electrode may be useful in the emergency management of acute bradyarrhythmias and for elective electrophysiological studies.

Adult↗

PubMed1995

An esophageal and gastric approach to ventricular pacing.

Using a unipolar esothoracic pacing system (where current passes from a point source positioned in the distal esophagus to a chest wall pad) and pulse duration of 50 msec, satisfactory 1:1 ventricular capture was obtained in 57 (86%) of 66 patients, with a mean threshold current of 27.7 mA at an optimal depth of 40.3 cm from the lower lip. When the unipolar esothoracic and bipolar transesophageal ventricular pacing systems were compared, the bipolar system was associated with a lower success rate and higher threshold current. When unipolar esothoracic pacing and gastrothoracic pacing (where current passes from a point source positioned in the stomach to a chest wall pad) were compared in 23 patients with bradyarrhythmia, ventricular capture was achieved using gastrothoracic pacing in 22 patients (96%) and esothoracic pacing in 21 (91%): gastrothoracic pacing required less current (16.0 mA +/- SD 7.2 vs 25.8 mA +/- SD 8.6). Optimal ventricular capture occurred using a unipolar gastrothoracic pacing electrode inserted to an average depth of 44.3 cm together with a high impedance chest pad (250 omega) placed in the fourth interspace at the left sternal edge, with 50-msec current pulses and a mean threshold of 16.0 mA. Thus, using a gastroesophageal electrode system, ventricular pacing can be achieved successfully, and the availability of such a system could play a major role in resuscitation of patients from severe bradyarrhythmias.

Bradycardia↗

PubMed1994

Use of the gastro-oesophageal route for the rapid establishment of ventricular pacing.

A novel approach to emergency ventricular pacing has been developed using a gastro-esophageal electrode. The polythene electrode was passed into the stomach, after which the electrode tip was positioned in the gastric fundus. Ventricular pacing was performed using a cathode mounted on the electrode tip; the indifferent electrode (anode) was either a chest pad or a proximal ring electrode. Ventricular capture was easily achieved in three emergency cases of severe bradyarrhythmia.

Adult↗

PubMed1994

Transesophageal electroventilation. Optimization and improvement.

For electroventilation, short duration pulse trains (0.1 ms) were applied between two axillary pads (transchest) and compared with transesophageal electroventilation where pulses passed between the same pads to an esophageal electrode in apneic, pentobarbitone-anesthetized pigs. Significantly greater tidal volumes were produced by transesophageal electroventilation in comparison with transchest. As measured by maintained tidal volumes, duration of inspiratory air flow, peak flow, percentage hemoglobin oxygen saturation (%SaO2), and end tidal carbon dioxide concentration (ETCO2), the optimal requirements for transesophageal electroventilation were pulse frequency 40 Hz, 0.7 s duration pulses, at 60 to 100 V, pulse width 0.1 ms, with the esophageal electrode proximal to the gastroesophageal junction without producing brachial plexus stimulation. The efficiency of transesophageal electroventilation falls off rapidly following ventricular fibrillation. Thus, the application of this technique would be in respiratory arrest with maintained circulation, eg, in drug-induced respiratory depression, severe smoke inhalation, severe emphysema, high cervical cord lesion, and weaning from prolonged mechanical ventilation.

Animals↗

PubMed1993

Transoesophageal versus transchest DC cardioversion.

Attempted cardioversion via the oesophagus (transoesophageal cardioversion) was compared with the transchest approach (transchest cardioversion) in a randomized trial of 100 consecutive patients with atrial fibrillation. For the transoesophageal group, 30, 50 and 100 J were delivered via an oesophageal electrode with subsequent 200 and 360 J transchest if required. For the transchest group, 50, 100, 200 and 360 J were delivered if required. In the transoesophageal group, 36/50 (72%) of patients cardioverted using the transoesophageal route alone, and in the transchest group, 41/50 (82%) of patients cardioverted (p = NS). First shock success was similar for the transoesophageal and transchest groups: 13/50 (26%) vs. 8/50 (16%) respectively. The mean number of shocks required to achieve successful cardioversion was identical for the transoesophageal and transchest groups (2.6). However, transoesophageal cardioversion was more successful than transchest cardioversion at energies < or = 100 J (36/50 [72%], and 17/50 [34%], p < 0.05). Median total energy for successful cardioversion was lower for patients in the transoesophageal group (180 J) than the transchest group (350 J) and mean peak current at successful cardioversion was also lower for patients in the transoesophageal group (21.7 A) than the transchest group (27.3 A) (p < 0.05). No oesophageal complications occurred. Thus, using an oesophageal electrode, cardioversion can be achieved as successfully as using the transchest route. The transoesophageal approach offers a low impedance, and consequently a low-energy pathway for cardioversion.

Atrial Fibrillation↗