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Biomedical subjects

D J Engle

Publications and source records attributed to D J Engle.

5 recordsLinked to original sources
PubMed1987

Brain tumor resection guided by intraoperative computed tomography.

Intraoperative computed tomography (CT) with a dedicated, therapeutic scanner facilitated resection of intracranial tumors in nine patients. Major benefits of intraoperative CT included exact, multiplanar lesion localization, maximal surgical resection and immediate recognition of potential intraoperative complications such as intracranial hemorrhage. Three cases are presented in detail to demonstrate the surgical technique. No complications related to the use of intraoperative imaging occurred. Although total resection of malignant brain neoplasms remained an unrealized goal, intraoperative CT increased the surgical accessibility of malignant and benign lesions located in critical areas of the brain.

Adolescent↗
PubMed1986

Rigid head fixation for intraoperative computed tomography.

A C-ring radiolucent head holder was designed to facilitate intraoperative computed tomography (CT) during resection of various intracerebral lesions. Important features of the procedure include rigid skull and CT table fixation, cranial access, and low artifact CT imaging performed during and after operation. A case of CT-assisted resection of an arteriovenous malformation is described.

Adolescent↗
PubMed1977

Feeding and drinking interactions after acute butyrophenone administration.

The effects on feeding and drinking of various doses of droperidol, haloperidol and spiroperidol were studied in a number of paradigms. All three buryrophenones produced generally similar effects. After food deprivation, feeding was slightly increased at low doses but was decreased at the higher doses; the concomitant postprandial drinking was attenuated at all doses. Desalivate rats showed a marked attenuation of feeding (and prandial drinking) at low doses, but when wet mash was given instead of pellets and water a normal dose-response relationship was obtained. After water deprivation drinking was attenuated at all doses, and when food was also available during the drinking test the food intake was decreased in proportion to the drinking. Drinking was blocked more when food was present than in its absence. Insulin and 2-deoxyglucose induced feeding in sated rats was attenuated but not abolished by haloperidol. The findings are discussed relative to the role of activation and brain catecholamines in feeding and drinking.

Animals↗
PubMedDate not supplied

Retroclival arachnoid cyst.

Retroclival arachnoid cyst is a rare mass lesion, with only seven cases previously reported in literature. MR is the imaging modality of choice in its evaluation and in its differentiation from epidermoid cyst. The case reported here was surgically proved and had an uncharacteristic MR signal intensity that was higher than that of cerebrospinal fluid due to previous hemorrhage.

Arachnoid Cysts↗