A micro technique for endotoxin assay by using Limulus lysate.
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Endotoxins↗
Biomedical subjects
D J Flowers
Publications and source records attributed to D J Flowers.
Antimycotic denture adhesive in treatment of denture stomatitis.
The mycologic findings of Candida albicans or culturally similar yeasts in 70% of the subject sample is consistent with those of other researchers. It is, however, only one of several etiologic factors requiring concomitant study to obtain meaningful results. Use of an antimycotic denture adhesive did not prove to be effective in the treatment of denture stomatitis. Although in the trial it appeared that marginally better results were obtained with the amphotericin medicated adhesive, this could not be substantiated statistically. On retrospective testing in the laboratory, both medicated and placebo materials were found to have an inhibiting effect on the growth of C. albicans. However, it was considered that the beneficial effects noted were probably due to the adhesive and lubricant effects of the test materials in reducing denture trauma in function.
Adhesives↗
Use of sensitivity discs as primary antibiotic standards in MIC determination.
A method for the determination of minimum inhibitory concentration (MICs) is described, in which commercially prepared antibiotic sensitivity testing discs are used as primary antibiotic standards from which the necessary dilutions are prepared in WHO Perspex haemagglutination plates. The materials required are readily available in most laboratories at a cost in time and reagents that compares favourably with most traditional methods of MIC testing. The same techniques may also be used to demonstrate combined antibiotic activity and to differentiate between bacteriostatic and bactericidal activity, with little expenditure of laboratory resources.
Gentamicins↗
Human infection due to Mycobacterium marinum after a dolphin bite.
A young man employed at the local aquarium was bitten by a bottlenose dolphin (Tursiops truncatus) during a training session, receiving a slight injury which healed rapidly. Some two months later fluctuant swellings appeared in the region of the bite, which developed into indolent ulcers which have not completely healed seven months after the original bite. Cultures taken on two occasions have yielded a pure growth of Mycobacterium marinum.
Adult↗