Biomedical subjects

D J Magelssen

Publications and source records attributed to D J Magelssen.

3 recordsLinked to original sources

PubMed1988

Benefits of posturethropexy bladder conditioning. Fact or fiction?

The influence of intermittent bladder catheter clamping upon detrusor tone in female postsurgical urethropexy patients was investigated. Thirteen patients who underwent retropubic urethropexy procedures were studied from March 1982 to December 1982. Utilizing a Corometrics 112 Fetal Monitor, intravesicle pressures were obtained in response to known volumes of saline solution instilled into the bladder. These measurements were obtained before and after the intermittent clamping sequence, which was carried out for a 24-hour period. No difference in bladder tone was noted when comparing prestudy to poststudy intravesicle pressures. Posturethropexy bladder conditioning failed to improve detrusor tone or bladder function in these patients.

Adult↗

PubMed1987

External cephalic version at term: is a tocolytic necessary?

This prospective investigation evaluates the benefit of a beta-mimetic tocolytic for external cephalic version. From July 1, 1984 to May 15, 1987, 58 patients who had breech presentations between 37-41 weeks' gestation were considered for external cephalic version. The patients were randomly assigned to one of two groups: tocolytic or no tocolytic. An ultrasound examination, serum alpha-fetoprotein (AFP), Kleihauer-Betke test, and nonstress test (NST) were performed before and after the attempt at version. A version was not attempted if there was evidence of intrauterine growth retardation (IUGR), oligohydramnios, or a nonreactive NST. Patients in the tocolytic group received 200 micrograms/minute of ritodrine hydrochloride for 20 minutes via continuous intravenous infusion before a version was attempted. Twenty of the 30 patients (66.7%) in the tocolytic group and 19 of the 28 patients (67.8%) in the no-tocolytic group had successful versions, a nonsignificant difference. The nine patients with unsuccessful version attempts in the group without a tocolytic then received intravenous ritodrine and underwent a second attempt. Only one of these nine attempts was successful. There were no serious maternal or fetal complications associated with the attempts at version. In our patient population, use of a tocolytic did not significantly increase the probability of a successful version.

Adult↗

PubMed1977

Conjugated estrogens and the overnight dexamethasone suppression test.

Basal (8:00 AM) serum cortisol levels in peri- or postmenopausal women treated with 0.625 mg daily of conjugated equine estrogens were only slightly higher than pretreatment levels. A 1.25 mg/day dosage resulted in a significant increase in basal serum cortisol levels. In women treated with either dosage, 8:00 AM serum cortisol levels 8 to 10 hours after 1 mg of oral dexamethasone were suppressed to below 5 microgram/100 ml, although there was a significant rise in post-dexamethasone serum cortisol levels in those treated with the higher dosage. It is concluded that while replacement dosages of estrogens increase circulating total serum cortisol levels, they do not interfere with the interpretation of the overnight dexamethasone suppression test.

Adult↗