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D J Pallot

Publications and source records attributed to D J Pallot.

50 records · Page 3Linked to original sources

Some histological and histochemical studies of the pancreas of the Brasilian sloth, Bradypus tridactylus.

The histological and histochemical study of the pancreas of the three-toed sloth, Bradypus tridactylus, demonstrated that with the methods employed the pancreatic islets are apparently formed by A cells exclusively. Two different types of argyrophilic cells were noticed in the exocrine secretory units when Grimelius' method was used. The methods for the demonstration of D cells showed negative results. Aldehyde fuchsin-positive granules were only noticed at the apex of the exocrine pancreatic cells. These results are discussed in relation to current hypotheses concerning the evolution of insulin secretion mechanisms.

Animals↗

Ultrastructure of the pancreas of Bradypus tridactylus.

The fine structure of the pancreas of the South American three toed sloth, Bradypus tridactylus, is described. In exocrine cells two types of granules are found. The first variety of granules is circular, of about 0.9 micrometer mean diameter, and probably represents zymogen granules. The second type of granule is larger (up to 1.4 micrometer in diameter) and contains a granular electron-dense material which is separated from the limiting membrane by a wide space. Only one type of islet cell was found. It contains spherical membrane-bound granules of uniform size.

Animals↗

Investigation of cranial and other nerves in the mouse with muscular dystrophy.

In the muscular dystrophic mouse mutant there is an absence of Schwann cells over circumscribed lengths of all cranial nerves except for II (I was not examined) and the lesion involves the sympathetic system. Where present, Schwann cells do not produce myelin of normal thickness. The lesion is similar to that described for the spinal roots. Causation is discussed.

Abducens Nerve↗

Some observatoons on the carotid bodies of the New Zealand strain of genetically hypertensive rats.

We report preliminary studies of the carotid bodies in the New Zealand strain of hypertensive rats. Female animals have a higher blood pressure than males of the same colony, but in both sexes mean arterial pressure is elevated significantly when compared to normal animals. The carotid bodies are enlarged in both the hypertensive and normotensive animals and there is no correlation between carotid body size and arterial pressure. The only structural abnormality detected in the hypertensive carotid bodies was a gross thickening of the intimal layer of the arterioles. The content of dopamine in the organs was similar in normotensives and hypertensives but the noradrenaline levels were some 50% lower in the hypotensives. These results are discussed and compared with data available for SHR animals.

Animals↗