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Biomedical subjects

D J Pender

Publications and source records attributed to D J Pender.

12 recordsLinked to original sources

The oronasal speculum.

The oronasal speculum is a standard nasal speculum with a metal tongue depressor incorporated into one of the handles. It permits the physician to examine the oral cavity and pharynx immediately after examination of the nose without changing instruments.

Equipment Design↗

Laryngismus fugax: transient laryngeal spasm secondary to brain stem ischemia.

Bilateral vocal cord immobility in adduction is an uncommon, yet potentially life threatening, disorder. Endolaryngeal and neuromuscular causes are well known and for the most part readily diagnosed by the otolaryngologist. Central neurologic etiologies are more unusual. A case of transient spastic laryngeal paralysis secondary to cardiac emboli and brain stem ischemia is presented. A mechanistic analysis suggests that this entity occurs in the setting of pseudobulbar paralysis, and that the ultimate ischemic event may be loss of glycine mediated inhibition of laryngeal motoneurons.

Adult↗

Otolaryngologica prevarica: Munchausen's syndrome update and report of a case.

Colorful lying is a central feature of Munchausen's, a syndrome well characterized despite an imperfect understanding of its psychiatric aspects. Reported otolaryngologic presentations are infrequent. A classic case is described in detail. A new name, "Otolaryngologica Prevarica," is proposed to maintain awareness of the entity in the specialty. The psychodynamics and the relation to sadomasochism, hysteria and malingering are discussed.

Adult↗

Chain-saw hazard.

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Accidents, Home↗

Gentamicin tympanoclysis: effects on the vestibular secretory cells.

Gentamicin application to the middle ear may relieve Meniere's disease, presumably by reducing endolymph secretion by the dark cells. To explore this possibility, the ears of adult cats were treated with daily intratympanic infusions of gentamicin until ataxia occurred. The temporal bones of these cats were then examined using electron microscopy. A 3 per cent solution of gentamicin resulted in ataxia after four treatments. Acute dark cell damage to basal infoldings seen after one month persisted at six months. Treatment with a 0.3 per cent solution required 15 and 21 days to effect ataxia and resulted in a similar damage pattern. Treatment with the 0.3 per cent solution for 13 days (i.e., before ataxia developed) resulted in subtle early lesions in the basal infoldings. Such lesions might affect the rate of endolymph secretion.

Animals↗

Cogan's syndrome.

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Hearing Disorders↗