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Biomedical subjects

D J Roebuck

Publications and source records attributed to D J Roebuck.

At least 19 recordsLinked to original sources

Ionising radiation in diagnosis: do the risks outweigh the benefits?

Every diagnostic test in medicine has costs and potential benefits. Doctors must ensure that the benefits of each test performed outweigh the costs, which include financial considerations and risks to the health of the patient. The possible adverse effects of some invasive tests such as biopsies may be well understood, but for others the risks are not so obvious or immediate. Seemingly "non-invasive" tests involve the use of ionising radiation and carry the risk of causing malignant tumours. This risk is widely underestimated in medical practice in Australia, and it is the responsibility of the radiological community to demonstrate that commonly performed investigations result in a net benefit to patients.

Costs and Cost Analysis

The role of imaging in renal and extra-renal rhabdoid tumours.

Rhabdoid tumour of the kidney is an uncommon malignancy with a poor prognosis that usually occurs in childhood. Certain imaging features may help distinguish this lesion from the much more common Wilms' tumour. Extra-renal rhabdoid tumours appear to have no specific imaging characteristics.

Biomarkers, Tumor

The use of ultrasound in the venous assessment of lower limb Klippel-Trenaunay syndrome.

Colour Doppler ultrasound was used to study the affected lower limbs of a group of patients with the Klippel-Trenaunay syndrome. The abnormal lateral venous channel characteristic of this syndrome was examined, together with its deep venous connections and deep venous patency established if present. Seventeen patients (18 limbs) were studied. Ultrasound demonstrated calf vein patency in 15 out of 17 limbs and deep venous patency from the popliteal vein to the inferior vena cava in 17 out of 17 limbs. Ultrasound was also effective in demarcation of the abnormal lateral venous channel, together with its deep connections (13 out of 16 limbs). We conclude that ultrasound is superior to the more established venographic techniques in the investigations of patients with the Klippel-Trenaunay syndrome. From this study, the deep venous aplasia said to occur in the condition would appear to be less common than previously thought.

Adolescent

Pictorial review: the imaging features of lower limb Klippel-Trenaunay syndrome.

The Klippel-Trenaunay syndrome is a rare mesodermal abnormality causing venous anomalies, cutaneous capillary naevi with bone and soft tissue hypertrophy of one or more limbs. In this pictorial review we illustrate the plain film, venographic, ultrasound and magnetic resonance imaging features of Klippel-Trenaunay syndrome affecting the lower limb.

Adolescent