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Biomedical subjects

D J Weider

Publications and source records attributed to D J Weider.

31 records · Page 2Linked to original sources

Bilateral congenital oval window microfistulae in a mother and son.

This article details case histories of a son and his mother who were studied over a seven-year period before making the diagnosis of bilateral oval window microfistulae in both of them. The boy demonstrated a slowly progressive bilateral and symmetrical sensorineural hearing loss closely resembling that of his mother. The case reports emphasize their respective histories, diagnostic evaluation, surgical observations, and treatment.

Adult↗

Audiologic findings in Charcot-Marie-Tooth disease.

An audiologic study of a 54-year-old patient with Charcot-Marie-Tooth disease whose initial symptom was hearing difficulty is presented. While findings from basic audiologic tests were not consistent with the degree of auditory difficulty reported by the patient, special testing did indicate a notable deficit. Although the auditory periphery was probably mildly involved, it seemed that the major auditory deficit was central.

Audiometry, Evoked Response↗

Use of the Williams microclip in various aspects of tymanoplastic surgery.

The microclip was invented by J. David Williams, M.D. in 1971 in an attempt to devise a technique to reliably secure a medially placed fascia graft to a tympanic membrane remnant. This method immediately improved the graft take rate to better than 90% in the Alaska native population with whom he was working. Included in this 90% and above category were many ears that demonstrated some degree of mucosal edema, granulation tissue, or mucopurulent discharge--referred to in this paper as the "wet ear." Anatomic and audiologic results of 286 consecutive otologic procedures requiring a tympanic membrane graft will be presented in which the Williams microclip has been employed to secure a medially placed graft. Attention well be devoted to both success and failure of the methods employed. Special attention will be given to the description of surgically challenging situations in tympanoplasty surgery such as "the narrow to non-existent remnent segment" where the microclip demonstrates its exceptional usefulness. Last, additional uses of the microclip (other than in tympanic membrane grafting) will be discussed including its application in a new technique of ossicular chain reconstruction. Case reports and statistical data will augment material presented.

Adolescent↗

Tympanoplasty: medial grafting using Williams' microclips.

A technique for medial grafting that evolved in Alaska over a period of about five years has been used by the author at the Dartmouth-Hitchcock Medical Center for over two years. The technique is one whereby fresh temporalis fascia is placed medial to the tympanic membrane remnant and fastened to that remnant with stainless steel wire microclips. This technique has resulted in a success rate in excess of 94% in the Alaskan "bush." In a private practice setting, the success rate has been slightly better than 97%.

Adolescent↗

Cogan's syndrome: acute vestibular and auditory dysfunction with interstitial keratitis.

Two patients with Cogan's syndrome had acute bilateral hearing loss and vestibular dysfunction. Interstitial keratitis was discovered by slit-lamp examination. Both cases responded to corticosteroid treatment. Immediate recognition of this syndrome and the institution of high-dose corticosteroid therapy should lead to resolution of the hearing loss in patients with Cogan's syndrome.

Acute Disease↗

Auditory brainstem response and eighth nerve lesions: a review and presentation of cases.

A review of salient features in the use of auditory brainstem response for the detection of eighth nerve lesions is presented. Three cases of acoustic tumors are discussed. These cases represent a normal pure-tone audiogram, one with a moderate loss, and one with no measurable hearing on the affected side. Interpretation of the auditory brainstem response in these cases is discussed in light of the various auditory brainstem response measures presented and the pure-tone audiometric data.

Adult↗

Reversible audiological results in a patient with an extra-axial brain stem tumor.

A case of a 32-yr-old patient with an extra-axial brain stem tumor is presented. Many postoperative audiological test results were reversed compared to the preoperative results. A variety of auditory measures were conducted to show which tests were sensitive to this patient's lesion. Also reported are some rather unique postoperative auditory changes which, in retrospect, provided an interesting view as to the extent of the lesion.

Adult↗

The auditory brain stem response I-V amplitude ratio in normal, cochlear, and retrocochlear ears.

The auditory brain stem response I-V amplitude ratio was measured for 25 normal, 25 cochlear, and 25 retrocochlear ears. Results indicated that amplitude ratios of less than 1.00 seldom occurred in the normal or cochlear ears. However, 44% of the retrocochlear ears revealed an amplitude ratio of less than 1.00. Details of this analysis and discussion of the clinical implications of these results are presented.

Adolescent↗

Lingual thyroid: review, case reports, and therapeutic guidelines.

The literature on lingual thyroid is reviewed. The incidence is relatively rare and sex incidence is four or five to one in favor of females. The embryology and development of the thyroid gland is discussed and some evidence presented to suggest that the lateral thyroid primordia are not involved in the formation of functional thyroid tissue. The pathologic findings of lingual thyroid tissue are similar to that of cervical thyroid tissue, including goiter formation. Diagnostic measures include mirror examination, I-125 scan, and tomography. Thyroid function studies are helpful in evaluating the level of thyroid function. Treatment includes surgical removal, transplantation, I-131, and thyroid replacement. Since the first three methods usually require supplemental thyroid treatment afterward, it is believed that initial thyroid replacement is the treatment of choice since it is simple, safe, effective, and noninvasive. Four new cases are reported.

Adolescent↗

Natural history of otitis media in the American native.

Otitis media is the leading reportable disease among the Indian and Eskimo population. In addition, its prevalence is more frequent in American natives than in Caucasians or Negroes. An attempt herewith is made to delineate the factors that account for the high prevalence of otitis media in the acute and chronic form. Secondly, the characteristic morbid complications of otitis media in this population are evaluated.

Adolescent↗