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Biomedical subjects

D Jinnai

Publications and source records attributed to D Jinnai.

At least 19 recordsLinked to original sources
PubMed1986

Second primary cancer following adjuvant chemotherapy, radiotherapy and endocrine therapy for breast cancer: a nationwide survey on 47,005 Japanese patients who underwent mastectomy from 1963-1982.

Out of a total of 47,005 cases of primary breast cancer with curative surgery recorded in Japan in the 20 year period from 1963 to 1982, 764, or 1.6 per cent had a second primary cancer occurring during the same period. The distribution of the second site was gastric cancer in 200 (26.2 per cent), breast cancer in 200 (26.2 per cent), colorectal cancer in 59 (7.7 per cent), cancer of the cervix uteri in 54 (7.1 per cent) and thyroid cancer in 37 (4.8 per cent). The gastric cancer was the Borrmann type 4, and the poorly differentiated scirrhous type. Incidence of the second cancer was enhanced, in the first period before 1971 and by contrast, in the second period after 1971 it was diminished. In the chemotherapy (+) group, the occurrence of the second cancer seemed to be strongly influenced by mitomycin C. In the radiotherapy prescribed group, leukemia was as frequent as esophageal cancer, and in those given endocrine therapy, breast cancer strongly inhibited the current one.

Antineoplastic Agents↗
PubMed1984

Synchronous and metachronous malignancies of the colon and rectum in Japan with special reference to a coexisting early cancer.

The authors reviewed the medical records of 1005 patients with multiple colorectal cancers (763 synchronous and 242 metachronous) to study the number and site of the tumors, their preoperative detectability, and the results of treatment. Concurrent advanced cancers were found in 35.1%, concurrent advanced and early cancers in 59.0%, and concurrent early cancers in 5.9% of patients with synchronous malignancy. In 60.1% of these patients, the existence of multiple lesions was diagnosed preoperatively; coexisting early cancers were often overlooked. In patients with metachronous malignancy, early cancers were less frequent than in patients with synchronous malignancy. The cumulative 5-year survival rate in curatively operated patients was 70.4% for synchronous malignancy and 66.5% for metachronous malignancy, similar to that for colon cancer in general.

Colonic Neoplasms↗
PubMed1983

Malignant lymphoma of the large intestine--operative results in Japan.

One hundred thirty cases of primary malignant lymphoma of the large intestine in Japan were studied with regard to operative results. The averaged age was 52.6 years and most of the patients were men. Sites of the tumor were the cecum (71.5 per cent), rectum (16.9 per cent) and the ascending colon (6.2 per cent). Surgery was performed for 129 (99.2 per cent) of the 130, of which 71 (55 per cent) were curatively resected. Surgical procedures were mostly Miles operation and the others were anterior resections and hemicolectomies. Postoperative 5 and 10 year survival rates were 34.8 per cent and 33.2 per cent respectively, and the rates after curative resection were 44.2 per cent and 40 per cent respectively. Prognoses were better when the tumor was of 5 cm or less in diameter, intraluminal and without lymph node metastasis. Classified histologically, most of the tumors were of histiocytic type, followed by lymphocytic, mixed type and Hodgkin's disease. Five and ten year survival rates of the curative resection group, by histological type, were both 38.9 per cent for histiocytic type, both 43 per cent for lymphocytic type, 43.8 per cent and 21.9 per cent respectively for mixed type, and both 100 per cent for Hodgkin's disease. Therefore, the operative result of malignant lymphoma in the large intestine was poor compared with results in case of cancer of the large intestine.

Adolescent↗
PubMed1975

Fifty years of cancer surgery of the large intestine at Osaka University Hospital.

Surgical procedures were performed in 863 cases of carcinoma of the large intestine in the Second Department of Surgery, Osaka University Hospital, Japan, between 1924 and 1973. There were 262 cases (30.3%) of carcinoma of the colon and 601 cases (69.7%) of carcinoma of the rectum. Sacral resection was the main procedure for rectal carcinoma until 1934. From 1954 through 1962, the abdominoperineal excision became predominant with radical operability 73.3%. Operative mortality declined to 2.3% and the five-year survival rate reached 52.1%. In 1963, sphincter-preserving operations were introduced, after which the radical operability increased to 76.1% and the survival rate to 56.8%. In these years, we selected cases for low anterior resection. Welch's invagination anastomosis and Bacon's pull-through operation according to each indication. For colonic carcinoma, the operative mortality was 2.2%, the five-year survival rate 63.2% and the ten-year survival rate 44.2% in the last period.

Adenocarcinoma↗