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Biomedical subjects

D K Mukherjee

Publications and source records attributed to D K Mukherjee.

14 recordsLinked to original sources

Neurilemmoma of the vagus nerve: a case report.

A CASE of an unusually big neurilemmoma arising from the vagus nerve in the neck is presented in this paper. The tumour was so big that it could not be removed until its size had been reduced by the removal of about 15 cc of its fluid contents. The patient had a cardiac arrest on removal of the tumour, denoting probable stimulation of the vagus nerve leading to vagal arrest. His heart started, however, after resuscitative measures and he has not shown any residual cardiac abnormalities, thus indicating that the main vagal trunk was undamaged.

Cranial Nerve Neoplasms

Chloroquine ototoxicity--a reversible phenomenon?

The case of a six-year-old girl suffering from severe cochleo-vestibular dysfunction following a series of chloroquine phosphate injections is presented in this paper. Prompt institution of therapy with steroids and vaso-dilators has helped to restore the hearing to a serviceable (socially acceptable) level. A surmise is made about the pathogenesis of chloroquine ototoxicity and how prompt appropriate therapy may be able to reverse the process. A plea is made for early referral of these cases so that prompt attention may be paid to them.

Child

Arterio-venous fistula of the ear.

A case of congenital arterio-venous fistula involving the external ear in a 33-year-old female patient is described in this paper. She presented to the hospital with severe haemorrhage from the swelling over the ear necessitating immediate admission into hospital and transfusion of whole blood. The treatment of the case is described in detail. She is alive and well 3 years after her definitive treatment.

Adult

Solitary tuberculoma of the larynx: a case report.

A case of solitary tuberculoma of the larynx in a 56-year-old man from Calabar, Nigeria, is presented. He had upper respiratory tract obstruction severe enough to necessitate a tracheostomy. It is suggested that tuberculoma of the larynx may not be as rare as a review of the currently available medical literature would suggest. More may be discovered if all cases of polypoid masses in the larynx, however innocent they look, are histologically examined.

Humans

Penetrating injury of the chest and coronary arteriovenous fistula.

An unusual case of coronary artery fistula, due to a stab wound in the chest in a 17-year-old male patient, with a resultant acute inferior myocardial infarction is presented. At surgery, complete transection of the right coronary artery was found, which formed a fistulous communication with both the right atrium and the right ventricle. The development of a continuous murmur in the period immediately after the injury, the absence of hemopericardium, and multiple cardiac-chamber involvements were unique features of the case. The inferior myocardial wall was akinetic due to infarction and did not improve following revascularization surgery. A brief review of the literature is also presented.

Adolescent

Tetanus and tracheostomy.

Forty-one patients with tetanus in different stages of the disease on whom tracheostomies were performed are discussed in this paper. Out of these, 21 died, giving a mortality rate of just over 50%, which is about equal with those reported from other centers. It was found that patients in Stage III of the disease referred for tracheostomy hardly ever recovered. Patients in Stage II on whom tracheostomy was performed early stood the best chance of survival and recovery. However, if the operation was delayed in Stage II patients, there was a much greater chance for complications to develop, mostly due to aspiration of secretions into the tracheobronchial tree with consequent bronchopneumonia. There were four deaths, all in Stage III patients undergoing tracheostomy, where no definite or conventional identifiable cause could be determined. There were three deaths due to "technical failure" in tracheostomized tetanus patients, which underlines the difficulties and technical problems encountered in satisfactorily maintaining a totally paralyzed patient without any means of communication.

Adolescent

Choriocarcinoma of the nose.

A case of choriocarcinoma in a 17-year-old unmarried female is presented. She attended the E.N.T. Clinic with a rapidly growing mass at the tip of the nose. Histologic report of the excised mass was reported as a secondary deposit from a choriocarcinoma. Further questioning at this stage revealed the history of an abortion two years before. Gynecological examination revealed secondary deposits in the vagina. X-rays of the chest showed evidence of metastases in the lungs. She died of profuse bleeding from the vagina.

Adolescent