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Biomedical subjects

D K Verlinskaia

Publications and source records attributed to D K Verlinskaia.

27 records · Page 2Linked to original sources

[Study of the level of lipids in the blood serum of patients with Shereshevsky-Turner syndrome].

A comparative study of serum cholesterol, total lipoprotein and triglyceride level in patients with the XO karyotype and in normal subjects (XX) showed cholesterol and total lipoprotein to be increased in these patients; as to triglyceride level--it proved to be unchanged. The type of hyperlipoproteinemia was established in 7 of 18 patients examined; all of them under 30 years old. Thus, the incidence of hyperlipoproteinemia in the XO patients was sharply increased; this seems to be related to the low estrogen level.

Adolescent↗

[Platelet serotonin absorption in Turner's syndrome].

Functional activity of platelets was studied in 20 patients with Shereshevsky-Turner's syndrome. There was revealed a significant rise of platelet serotonin (5-hydroxytryptamine) content and also a reduction of exogenous serotonin absorption by platelets. The noted disturbances pointed to dysfunction of these cells, this serving as an auxiliary factor pointing out that the ageing process involved the blood elements. Reduction of platelet functional activity in patients with monosomia X was apparently due to chromosomic unbalance and with the associated hormonal control disturbances.

Absorption↗

[Osmotic stability of erythrocytes in Turner's syndrome].

Osmotic stability of erythrocytes was determined in 11 patients with Shereskevsky-Turner's syndrome and in 11 practically healthy persons. There was revealed an increased sensitivity of the patients' erythrocytes to the hypotonic NaCl solutions in comparison with the population of erythrocytes in control. Analysis of the age composition of the red blood cells demonstrated an increase in the number of young and old forms with an inadequate quantity of mature cells, this serving as a characteristic feature of the red blood in ageing. The results presented serve as an additional fact pointing to early ageing of patients with the Shereshevsky-Turner's syndrome.

Adolescent↗