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Biomedical subjects

D Kósa

Publications and source records attributed to D Kósa.

8 recordsLinked to original sources

[Successful treatment of hyperthyroidism simulating acute abdomen and psychosis].

A 49 years old female patient entered the surgical department because of epigastric and ileocoecal pains with the symptoms of acute abdomen. A surgical intervention was performed because of supposed appendicitis, but it was not verified. During the surgical observation the patient was confused and negativistic so she was transferred to the psychiatric department. Because of loss of 20 kg weight, high blood sedimentation and anaemia she was sent to our department with the suspicion of an organic disease. A moderate exophthalmos, glittering eyes and Graefe's sign was noted, therefore hyperthyroidism was diagnosed, which was proved by Kocher's blood picture, low serum cholesterol, extremely high T3 and T4 level, and iodine storage diagram. The antithyreotic treatment resulted a dramatic improvement in the extremely serious moreover hopeless case and after a long-term treatment the patient became symptom-free without complaints. Later because of regression of hyperthyreoidism and the growing nodular goitre the patient was treated on two occasions with radioactive iodine. At present the patient is in remission.

Abdomen, Acute↗

[Hyperparathyroidism simulating severe hypercalcemia syndrome].

The case history of a 65 year old female patient has been reported here by the authors. The patient was admitted to the Intensive Therapy Unit owing to her repeated heart pain. Later she was transferred to the Department of Medicine to establish the exact diagnosis. Prepyloric ulcer and hypertension were occurred in her history. The symptoms of her preceding as well as her recent illness were: pain in epigastric field, nausea, adynamia, weakness, polyuria, significant loss of weight, somnolence and the shortened Q--T time in electrocardiogram related to hypercalcemia syndrome. The calcium value in blood proved to be at critically high level from time to time. The possibility of the secondary hypercalcemic state was excluded by sonographic examination and the elevated level of parathormone in blood established the diagnosis of the hyperparathyroidism. The surgical resection of parathyroidic adenoma yielded a complete recovery of the patient. The authors call the attention to the significance of the clinical signs in the diagnosis of the disease.

Aged↗

[The local treatment of ozaena with streptomycin and novocaine (author's transl)].

The essence of this treatment is the injection of a mixture of 250 mgm of streptomycin (5 ml) and novocaine 1% (5 ml) on alternate days. The 10 ml mixture was injected into the conchae and submucosally into the septum on either side. Cure generally required a total of 2--3 gm of streptomycin over 15--20 days. Review of 25 cases treated over the past 15 years showed that 44% became symptom free and "good" results occurred in another 40%. In 16% treatment proved ineffective. Rehabilation was manifest by relief of subjective symptoms and disappearance of crusting and foetor. Atrophy remained irreversible.

Humans↗