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Biomedical subjects

D Klinter

Publications and source records attributed to D Klinter.

3 recordsLinked to original sources

[New transportable CPAP respiratory aid].

A mobile respiratory aid has been developed for a 7-year-old child in cooperation with the Institute for Electromechanical Construction of Darmstadt Technical University. Born prematurely in week 27 with bronchopulmonary dysplasia, she has thus been enabled to leave the ward without any major technical difficulties, opening up numerous opportunities for development to the child notwithstanding her continuing dependence on the breathing aid. The robust, handy device weights less than 10 kg, and is housed in an aluminum case the size of a briefcase. It is battery-driven, a charging lasting for some 7 to 8 hours of operation. All parts subject to wear, such as filter, tubings, and bellows, are commercially available through the medical equipment market. Reported is a period of use of more than 2000 hours, and it is hoped that other pediatric centres looking after children with similar problems will cooperate in further developing this mobile CPAP respiratory aid.

Activities of Daily Living↗

[Clinical picture and pathophysiology of elevated intracranial pressure].

In 48 children who had raised intracranial pressure (icp) this was monitored continuously by an epidural route. Icp-values were correlated with other important parameters like the mean arterial pressure (map) and the early components of brainstem acoustic evoked responses (BAER). The results were as follows: 1. focal and multifocal brain lesions resulting in vasogenic brain edema have better prognosis than those morbid conditions causing cytotoxic edema. In the letter group the whole brain's metabolism is impaired, brainstem, cerebellum and spinal cord included. 2. by monitoring map and icp we are enabled to assess the cerebral perfusion pressure. If this value falls short of 20 Torr the duration of unconsciousness and the frequency of brainstem related symptoms increases as well as impairment of cranial nerves and cerebellar-extrapyramidal symptoms and mental handicaps in the long term course. 3. cerebral dysfunction and organic brain syndromes in general are not related to icp-increase. They resemble local brain damage, e.g. after contusions. 4. serial registration of BAER is a good aid in iatrogenic induced deep phenobarbital coma. If there are critical values of the perfusion pressure mainly the waves III and V of BAER have increased peak latencies and go flattened. This trend takes place slowly within hours or even days. Loss of the components III and V is prompted by an irreversible damage of the caudal brainstem. This finding after cytotoxic brain edema is even more relevant than after vasogenic edema. If the component loss III-V is bilateral dissociated brain death has to be anticipated. Some important issues of icp-pathophysiology are discussed according to the literature.

Brain Injuries↗

[Fetal hydrothorax].

Three cases of bilateral congenital hydrothorax concomitant with hydrops fetalis are presented and compared with similar cases in literature. The hydrops fetalis to our opinion is caused by peripheral hypoxia. The hypoxia has its origin in the restricted cardiac output caused by the bilateral hydrothorax.

Amniocentesis↗