Prospective investigations of the managing staff in plant of heavy industry with respect to ischemic heart diseases.
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Biomedical subjects
Publications and source records attributed to D Knapikowa.
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We examined 81 men exposed for a long time to carbon disulphide (CS2) and tested the possible electrocardiographic (ECG) changes of ischemic heart disease (I.H.D.). The subjects were examined twice in two years. In order to make the ECG evaluation more objective, the Minnesota Code was applied. Two obligatory ECG examinations and only one submaximal effort test were carried out. For comparative evaluation, the control group was examined once. We proved that, in spite of the accepted opinion concerning the atheromatous action of CS2, this compound does not cause ECG symptoms of I.H.D. in a higher percentage of exposed persons. It also does not cause any significant increase in I.H.D. symptoms in dynamic ECG observations.
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This paper describes the basic concept of a multistage classifier and gives the results of the application of this approach to the diagnosis of vibratory syndrome and other diseases with similar symptoms. The multistage classifier was applied to classification of the most informative symptoms at particular stages of classification.
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The level of alpha 1-antitrypsin in blood serum in copper miners was examined. Among 278 subjects not a single case of total insufficiency was found, whereas the partial insufficiency of this inhibitor was found in 4.3% of subjects. The studies of the total correlation indicated high indices of the ratio between alpha 1-antitrypsin level and lungs vital capacity in those with bronchitis, which would suggest that the decreased efficiency of the respiratory tract results form the hereditary insufficiency of this inhibitor.
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