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Biomedical subjects

D Knasiak

Publications and source records attributed to D Knasiak.

4 recordsLinked to original sources

[Physical and biological examinations of polyester electret foil. Preliminary report].

The results of tissue reaction to polyester thermoelectret foil samples are evaluated. The electrostatic measurement of the foils was performed before implantation. The experimental animals were divided into four groups depending on the surface charge density of the foils. The autopsy of the animals was performed three days after the operation. The tissues of close contact to the foil were examined under the microscope and the electrostatic measurement of the foils.

Animals↗

Basic studies on autogenized and lysophilized vascular prostheses.

In an effort to improve vascular prostheses, basic studies on tissue-alloplastic prostheses according to a new conception were performed. A medical polyester yarn was used for the construction of three types of prostheses with different mesh and high porosity. The prostheses were autogenized on silicon rods and then lyophilized, resulting in their full intraoperative impermeability, but high biological permeability and antithrombogenicity. Vascular prostheses of this type fulfill many of the requirements of a so-called ideal prosthesis. Analysis of the test examinations provides a basis for elaborating principles for the preparation and production of new tissue-alloplastic prostheses for clinical purposes.

Bacterial Infections↗

[Use of biological methods in the testing of extracts of plastics (preliminary report)].

In the first part of the paper the problem of toxicological testing of medical plastics is discussed. Particularly attention was given to the biological testing of extracts of plastics. The results of own investigations on the toxicological testing of extracts in water for injection of three types of polyester vascular prostheses, two types of technical rubber and one type of silicon caouthouc are presented. The author presents a proposal of a new testing method for the toxicological evaluation of extracts in water of medical grade plastics utilizing diluted fresh bull's sperm. The results of the preliminary investigations on different materials proved the bull's spermatozoons to be sensitive to even small qualities of toxic substances composed in various medical grade plastic fabrics. In the author's estimation, there is a good reason to ascertain, that the presented method will be a new biololgical test destined to the preliminary evaluation and the current check-up of plastic medical materials.

Animals↗