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D Knop

Publications and source records attributed to D Knop.

3 recordsLinked to original sources

White blood cell-reduced platelet concentrates prepared by filtration using the Sepacell PL 5 II/10 II filter.

The further developed adsorption filter Sepacell PL 5/10 II has been evaluated for the white blood cell (WBC) removal from platelet concentrates (PCs) collected using a blood cell separator Fresenius AS 104 (F) or Haemonetics PCS Plus (H). Filtration was carried out according to the manufacturer's instructions by gravity and flow rates of 40-50 ml/min (BT Blood Banking) or 3-5 ml/min (AS Bedside). Mean post-filtration WBC contents under blood bank conditions were (5.63 +/- 6.44) x 10(5) (H) and (0.30 +/- 0.18) x 10(5) (F) for the PL 5 II filter and (3.32 +/- 4.23) x 10(5) (H) and (0.23 +/- 0.05) x 10(5) (F) for the PL 10 II filter; under bedside conditions with low flow rates: (1.31 +/- 1.71) x 10(5) (H) and (0.23 +/- 0.01) x 10(5) (F) for the PL 5 II filter and (0.36 +/- 0.13) x 10(5) (H) and (0.23 +/- 0.01) x 10(5) (F) for the PL 10 II filter. The results suggest that the WBC removal and log reduction correlate with the rates of WBC content of the PCs, the capacity of the filters and the flow rates.

Cytapheresis↗

[Does a single oral dose of famotidine influence the blood alcohol level?].

Six healthy volunteer medical students (three men and three women) on four separate occasions drank 500 ml of beer or 250 ml of white wine 30 min after having taken 40 mg of famotidine or a placebo (after 48 hours of abstinence and six hours of fasting). Administration of drug or placebo followed a double-blind, randomized protocol. There was no demonstrable effect of famotidine on the serum level of alcohol (maximal values 0.29-0.67 mg/dl) or on the time until maximal serum concentrations of alcohol were reached.

Adult↗