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Biomedical subjects

D Kohn

Publications and source records attributed to D Kohn.

At least 181 records · Page 10Linked to original sources

Arthroscopy in acute injuries of anterior cruciate-deficient knees: fresh and old intraarticular lesions.

Sixty-four patients out of a much larger population who presented within 2 weeks of an acute injury to the knee were found at arthroscopy to have either a chronic tear or chronic incompetent anterior cruciate ligament (group I, 32 patients) or to have an acutely torn anterior cruciate ligament (ACL) (group II, 32 patients). Arthroscopy of both groups allowed the author to compare and contrast the lesions found in each group. Chondromalacia of the femorotibial joint is significantly more frequent in chronic ACL-deficient knees (p less than 0.05), and there is a tendency to degenerative meniscus lesions and chondromalacia patella in these knees too.

Adolescent↗

The use of conventional ventilators for high frequency positive pressure ventilation.

Ten randomly selected patients were ventilated for defined periods with 2 ventilatory modes: (a) high frequency positive pressure ventilation (HFPPV) (frequency 66-70 min; tidal volume 1-3 ml/kg body weight), (b) conventional IPPV (frequency 16/min; tidal volume (VT) 10-15 ml/kg). This was done successfully using conventional ventilators, and keeping other variables (FIO2, PEEP) constant. Various ventilatory and hemodynamic variables were measured and compared during both modes of ventilation. The most prominent finding was a considerable reduction of cardiac output (CO) and stroke volume (SV) during intermittent positive pressure ventilation (IPPV) compared with HFPPV. Peak tracheal pressure was significantly lower during HFPPV. An increase in mean systemic arterial pressure and in oxygen transport was observed during HFPPV, whereas transpulmonary shunt and pulmonary vascular resistance (PVR) decreased during HFPPV. These findings are in accordance with previously reported advantages of HFPPV, and might be of importance in the treatment of patients with bronchopleural fistula, adult respiratory distress syndrome (ARDS), left ventricular failure and other conditions in which conventional positive pressure ventilation (PPV) fails.

Adult↗

Schönlein-Henoch syndrome in patients with familial Mediterranean fever.

Ten episodes of Schönlein-Henoch purpura (SHP) in 8 patients with familial Mediterranean fever (FMF) were observed. Five episodes developed 3-14 days after penicillin injections, suggesting an etiologic association. FMF and SHP have clear clinical similarities, and if the frequency of association of the 2 diseases is indeed high, perhaps a common etiologic factor should be sought. An immune complex mechanism might be the link between these 2 disease entities.

Adolescent↗