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Biomedical subjects

D Kostić

Publications and source records attributed to D Kostić.

At least 19 recordsLinked to original sources
PubMed1989

[Recurrent varices after surgical treatment].

Authors showed 240 patients with post-surgical, recidive varices. The cause of these varices were: perforators incompetentions, bad safeno-femoral deconnection, non extirpated collateral veins etc. Diagnosis of these complications is based upon Doppler and phlebographic examinations. Surgical treatment is based upon pathophysiological and pathoanatomic substrate (extirpation varices, subfascial ligature or discision perforators, etc).

Humans↗
PubMed1978

Characteristics of the brain tissue disialoganglioside G2a.

Disialoganglioside G2a was separated by one dimensional two-step TLC between the two ganglioside fractions using long plate precoated with silica H+ florisil in the particular solvent system. Behaviour of this fraction to the enzyme effect and molecule percentages of its components showed the characteristics of the ganglioside containing two N-acetylneuraminic acids. Synthesis dynamics of this fraction in rat brain was very intensive in the myelination period and it practically ended in 40th day. In mutant "Jimpy" mice brain ganglioside G2a served as an indicator of the normal ganglioside synthesis in relation to the changes in myelin sphingolipid molecular structure. Comparative brain studies undertaken in various species, intracellular rat brain fractions, various structures of Torpedo ocellata electric fish, emphasized the importance of this ganglioside in cell membrane formation where it is obligatory component. Quantitative determination of this fraction in Astrocytoma with various malignancy degree offers great help in differential diagnosis.

Aging↗
PubMed1976

[Rupture of the duodenum due to blunt injury].

Injuries of the duodenum, although rare, have increased in frequency of occurence during the past ten years. Careful attention must be given to them, especially if the injury was brought about by a blunt blow of the abdominal, and lower thoracic regions. X-rays are the most important means used in diagnosing such cases. Injuries of the duodenum often occur along with injuries of other related structures, especially in polytraumatized patients. Early diagnosis, and surgical treatment are conditio sine qua non for successful results. During the operation itself, a compete inspection of the entire duodenum, both intra and extraperitoneal parts, careful placement of sutures about the perforation and an exact drainage are of utmost importance in the prevention of postoperative complications. In cases in which the duodenal wall has lost its vitality for accepting suture, a gastrojejunal, duodenojejunal anastomisi, or gastrostomia are performed, the content of the duodenum is aspirated, the duodenum is decompressed and adequate drainage of the peritoneal cavity is established. In cases of accompanying injury of the pancreas, or choledochus, a drainage of the extrahepatic bile duct is recommended. The authors discuss one case with a ruptured duodenum, resulting from blunt trauma, in which all of the above mentioned procedures were used; they insist that any suspicion of a duodenum's rupture indicates an immediate laparotomy.

Duodenum↗