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Biomedical subjects

D Krŭstev

Publications and source records attributed to D Krŭstev.

6 recordsLinked to original sources

[Gastroduodenitis and ulcers--statistical study for 1998].

The ulcer disease is a chronic, cyclical and recrudescing illness, based on disturbing of the regulatory mechanisms of the stomach and duodenum. The ulcer disease is one of the social significant illnesses of our century, because approximately 10% of the people at least once in their life have clinical symptoms of ulcus duodeni.

Anti-Bacterial Agents↗

[The topographic anatomical aspects of some kidney anomalies].

On 50 cases of the dissecting material of the Department of Anatomy and Histology were worked out the kidney's vessels, the basin and the ureters, as the varieties in number and situation of the vessels, the cases of nephric ectopy and comparatively rare case of combined anomaly as well were traced and described. This anomaly is expressed in bilateral nephric ectopy, bilateral double ureter, which begins from independent calices set, and four pairs of polar kidney arteriae, which are situated bilateral as well. In the right they pass before v. cava inf. The vessels are equally calibrated, as the three pairs are branches of aorta abdominalis and the fourth of a. iliaca comm. The cases which were described attract the surgeons' interest because the zone of the kidney, its vessels and the way of the ureter are an object of frequent surgical interventions.

Arteries↗

[Diaphragmatic hernias--the clinico-anatomical aspects].

The present research has been taken over 56 cadavers from the dissecting material of the Department of Anatomy and Histology in the time of four dissecting courses. Tissue defects of the diaphragma with or without diaphragmatic hernias has been searched for. Also it has been followed the frequency of the sliding and the paraesophageal hiatus hernias. The tissue changes has been carefully described. In 12 of the cases it has been determinate defects of the diaphragma, as in two of the cases has been found parahiatal hernias as well. In 7 of the cases it has been found relatively wide hiatus esophageus, as 3 of them were accompanied with hiatus hernias. It has been determinate one case with combined defect--hiatal and parahiatal hernia. It has been discuss the possible reasons for their appearance and simply anatomical aspects of the surgical correcting techniques, which are known to us.

Diaphragm↗

[Retinoic acid--a teratogenic factor in caudal dysgenesis. Experimental models and hypothesis for pathogenesis].

Using teratogen--trans-retinoic acid (Sigma Chemical)--caudal malformations are experimentally induced in mice of the Spriche-Dolly breed. For the purpose the aforementioned reagent is injected into pregnant mice at 6-hour intervals dose 29 mg/kg. In stages between two and four paired somites, supravital staining with Nile blue sulfite (in 1:50,000 Ringer solution at 37 degrees C for 30 min) is done, followed by histological assessment of tissue sections. The malformation noted are summed up in an attempt to draw conclusions about their presumable pathogenesis.

Animals↗

[Invasive aspergillosis in patients who died from acute leukemia].

The necropsy material with acute leukosis (166 deceased) was studied in order to establish the incidence of invasive aspergillosis. It was established in 16 of the deceased (9,64%): aspergillosis pneumonia--in 5 cases, aspergillosis sepsis--in II, with invasion of lungs, brain, spleen, liver, myocardium and other organs. Clinically aspergillosis was not distinguished. Continuous septic temperature, not influenced by antibiotic therapy should draw the attention to the presence of aspergillosis. The factors, preconditioning aspergillosis infection are stressed upon: immune-suppressive treatment in acute leukosis, granulocytopenia, continuous preceding antibiotic therapy, etc. The difficulties in the clinical differentiation of the infection are emphasized. With a view to the high incidence and lethality of aspergillosis in acute leukosis, the introduction of modern diagnostic methods and treatment are underlined to be necessary.

Acute Disease↗