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Biomedical subjects

D Krajewska

Publications and source records attributed to D Krajewska.

9 recordsLinked to original sources
PubMed1979

Contact sensitivity to phenylglycidyl ether.

From among 40 workers with dermatitis who did not have contact with phenylglycidyl ether but worked with epoxy resins, 5 were positive to Epidian 5 and phenylglycidyl ether. Cross reactions between these contactants were noted in 3 of the 17 guinea pigs with primary sensitization to epoxy resin or the tested diluent. For 58 persons coming into contact with phenylglycidyl ether the frequency of sensitization to the contactant was determined and the mean period between starting work and the occurrence of dermatitis was calculated.

Animals↗
PubMed1978

New contact allergens and allergen sources.

In the report new contact allergens and allergen sources detected in Warsaw in the period 1975-1977 are described. They are divided into 3 groups: industrial allergens, remaining occupational allergens and cosmetics. There are given some data concerning the substances present in industrial oils, hardeners and epoxy resin solvents, drugs sensitizing nurses, several new sources of chromium allergens, essential oils and synthetic flavours. Results obtained with various star anise oil samples are described. Essential oils and synthetic flavours. Results obtained with various star anise oil samples are described. Essential oils and synthetic flavours are discussed as the main allergens in cosmetics.

Allergens↗
PubMed1977

Sensitivity to m-phenlenediamine.

Primary contact sensitivty to m-phenylenediamine was noted in 8 of 182 workers handling this substance as hardener. In these patients the period between the beginning of this work and the appearance of dermatitis was shorter if they became simultaneously sensitive to epoxy resin and/or triethylenetetramine. Moreover from among 150 consecutive patients one was positive to m-phenylenediamine and negative to p-phenylenediamine. From among the selected patients positive to p-phenylenediamine more than 40 per cent were also positive to m-phenylenediamine. A large number of the latter patients were as well positive to o-phenylenediamine. No patients were found who would be positive to o-phenylenediamine and negative to m-phenylenediamine. Nearly all those positive to m- and p-phenylenediamine were also positive to the meta isomers of other aromatic amines.

Dermatitis, Occupational↗
PubMed1977

Core region in Proteus mirabilis lipopolysaccharide.

Four R mutants of P. mirabilis were isolated. The composition of their degraded polysaccharides (PS) obtained from the respective lipopolysaccharides (LPS) as well as the composition and properties of the PS-fractions separated by column chromatography were examined. The results were compared with those obtained with PS of the wild type. One of the mutants could be classified as an Ra-type mutant, presenting a complete LPS core. This polysaccharide core contains: galacturonic acid, glucosamine, glucose, D-glycero-D-mannoheptose, L-glycero-D-mannoheptose in a molar ratio of 1 : 1 : 1 : 1 : 2 and 2-keto-3-deoxyoctonate. Taking into consideration the common sugars described previously in the LPS chemotypes of P. hauseri, the composition of the complete core region mentioned above represents the LPS core part of all the chemotypes, containing two different heptoses.

Bacteriophage Typing↗
PubMed1976

Sensitivity to epoxy resins and triethylenetetramine.

The present studies concerned 31 work sites in eight factories at which 422 persons were employed. In the course of seven years there were 126 cases of dermatitis, 99 of whom were patch-tested. Positive reactions to epoxy resin and/or to triethylenetetramine were found in 65.7% of the subjects. The aetiology of the other cases is discussed. Some of the patients who were positive to epoxy resin were tested with Bisphenol A and modified resins with blocked epoxy groups. The latency period of dermatitis and the localization were recorded, as well as the influence of the season and of certain working conditions on the occurrence of sensitization. Of the 80 patients who changed their occupation, there were relapses in 50 within one year. Relapses were more frequent in persons who continued to work with epoxy resins for more than three months after the appearance of dermatitis and in those simultaneously sensitive to allergens in the standard series.

Dermatitis, Contact↗
PubMed1976

Cross-reactions between ethylenediamine, diethylenetriamine and triethylenetetramine.

A consecutive series of 1544 patients and 137 patients in occupational contact with epoxy resins were tested with ethylenediamine and/or triethylenetetramine; some were tested with diethylenetriamine. Guinea pigs sensitized to triethylenetetramine were tested with ethylenediamine and diethylenetriamine. The results showed that cross-reactions may occur between triethylenetetramine and ethylenediamine, although the majority of the patients were sensitized to only one of the compounds.

Allergens↗