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Biomedical subjects

D L Blakey

Publications and source records attributed to D L Blakey.

7 recordsLinked to original sources

Interruption of hepatitis B transmission by modification of a gynaecologist's surgical technique.

Between January, 1979, and January, 1980, hepatitis B developed in three women within 6 months of their undergoing gynaecological surgery at a community hospital in Mississippi. Subsequent investigation revealed another case of hepatitis B associated with gynaecological surgery. The gynaecologist who carried out all four operations (gynaecologist A) was a chronic carrier of hepatitis B. Hepatitis B surface antigen subtyping on serum from gynaecologist A and from one of the hepatitis B patients gave identical results. Patients of gynaecologist A who underwent total abdominal hysterectomies or bilateral salpingo-oophorectomies were at a greater risk of acquiring hepatitis B than were patients in whom the same procedures were carried out by a control group of gynaecologists. After gynaecologist A modified his surgical technique and began wearing two pairs of gloves during surgery, there was no further hepatitis B transmission to his surgical patients.

Carrier State↗

Concurrent evaluation of epidemic St. Louis encephalitis: are you on the upward or downward side of the curve?

Laboratory confirmation of reported cases of St. Louis encephalitis (SLE) lags 2-4 weeks behind onset of illness. A review of our experience in Mississippi in 1975 and 1976 suggests that plotting the number of reported suspects greater than or equal to 50 years of age by date of onset and adjusting for reporting delays can help determine when the peak of the epidemic has passed. This method circumvents the obligatory delay of serologic tests, minimizes the bias of publicity and intensive surveillance, and may avoid promoting control procedure which are expensive, dangerous, and of uncertain efficacy.

Adolescent↗

Cutaneous sporotrichosis in forestry workers. Epidemic due to contaminated Sphagnum moss.

In December 1975 and January and February 1976, an epidemic of cutaneous sporotrichosis occurred in Mississippi among forestry workers and other persons exposed to sphagnum moss used in packing pine seedlings. Seventeen cases were identified, 15 of which were from patients who had been exposed to sphagnum moss from a single source. Attack rates were significantly higher among workers exposed to this moss than among those not exposed. Sporothrix schenckii was cultured from the implicated batch of sphagnum moss but not from other batches. The source of contamination of the sphagnum moss that caused this epidemic and sphagnum moss associated with similar epidemics is unknown. One worker without cutaneous sporotrichosis may have had asymptomatic pulmonary sporotrichosis.

Agricultural Workers' Diseases↗

St Louis encephalitis. The 1975 epidemic in Mississippi.

In 1975, 229 laboratory-documented cases of St Louis encephalitis, 36 of which resulted in death, occurred in Mississippi. A total of 58% of these persons had encephalitis, 15% had aseptic meningitis, 21% had a febrile illness with no known CNS involvement, and 6% had other syndromes. Attack rates and case-fatality ratios increased with age. Although 60% of the cases occurred in a four-county area of northwest Mississippi, cases occurred in 42 of the 82 counties throughout the state. The epidemic erupted almost simultaneously, with variable intensity, in widely separated areas. Mosquito-control, measures were applied, but the results were not quantified.

Adolescent↗

St. Louis encephalitis: clinical and epidemiologic aspects, Mississippi, 1974.

During July, August, and September 1974, 23 confirmed or presumptive cases of St. Louis encephalitis occurred in Mississippi. Attack rates were highest in the northwest corner of the state and among persons over 70 years of age. Rural and urban residents had similar attack rates. Nine persons have not resumed their pre-illness level of activity because of residual neurologic impairment six months after their illness. Additional cases of St. Louis encephalitis are expected in the next few years.

Adult↗