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Biomedical subjects

D L Boase

Publications and source records attributed to D L Boase.

13 recordsLinked to original sources
PubMed1992

Endophthalmitis following extracapsular cataract surgery: a review of 32 cases.

Thirty two cases of endophthalmitis following extracapsular cataract surgery that had occurred within our department and had undergone intraocular diagnostic tap between May 1982 and May 1991 were reviewed. An infectious agent was identified in 20 cases (62.5%). The commonest organism was Staphylococcus epidermidis (11 cases) (55%). Proteus was the only gram negative organism identified (four cases) (20%). Both of these organisms were associated with a favourable visual outcome. In the culture positive subgroup 15 eyes (75%) achieved a final acuity of 6/60 or better with 10 eyes (50%) gaining 6/12 or better. Thirteen (65%) of the culture positive cases were managed without vitreal intervention. Of these 11 (85%) achieved 6/60 or better with eight (62%) gaining 6/12 or better. It appears that when an endophthalmitis follows uncomplicated extracapsular cataract surgery delivery of antibiotic by the 'conventional' routes (topical, subconjunctival and systemic) is consistent with a favourable visual result in many cases. A modified anterior chamber diagnostic tap technique is described.

Adult↗
PubMed1989

How clean is your capsule?

Proliferation of residual lens epithelial cell is believed to be the major cause of posterior capsule opacification following extracapsular cataract extraction. During surgery these cells can be visualised with appropriate illumination facilitating their mechanical removal with the McIntyre cannula. When flat preparations of the anterior capsule are examined by light microscopy, the areas 'cleaned' of cells in this way appear transparent but scanning electron microscopy reveals tufts of remaining debris which may represent points of cellular attachment to the capsule. Control of lens epithelial cell proliferation is important for the future development of cataract surgery.

Cataract↗
PubMed1989

Accuracy of routine intraocular lens power calculation in a district general hospital.

To assess the accuracy of routine preoperative biometry we reviewed all cases of extracapsular cataract extraction with posterior chamber implant performed at Queen Alexandra Hospital in 1985. Of 471 eyes included in the survey 67.9% were within 1.0 D of the expected refraction and 90.7% within 2.0 D. Factors influencing accuracy are discussed. The necessity of routine preoperative biometry is emphasised.

Biometry↗
PubMed1980

Oxygen dissociation curve in Eales's disease.

The oxyhaemoglobin dissociation curve (ODC) was investigated in 15 patients with Eales's disease and 11 controls to test the hypothesis that Eales's disease is caused by retinal hypoxia secondary to impaired oxygen release from the blood. Patients with the peripheral form of Eales's disease did not have any significant difference in the P50 values when compared with the controls. However, the P50 values were significantly lower (P < 0.005) for the patients with mixed retinopathy. This degree of increased oxygen affinity is not physiologically significant but may reflect an intrinsic abnormality of the red cells in these cases.

Adult↗
PubMed1977

Results of closed vitrectomy.

The results of 101 closed vitrectomy operations are reported. The cases were classified on morphological grounds, and analysis showed that eyes with anterior segment or pure gel pathology responded favourably to surgery, while those with associated retinal disease had a poorer prognosis.

Eye Diseases↗
PubMed1976

Slipping of the upper femoral epiphyses in patients with intracranial tumours causing hypopituitarism and chiasmal compression.

Four cases of slipped upper femoral epiphyses in patients with intracranial tumours causing hypopituitarism and chiasmal compression are presented. Detailed endocrine studies in three cases showed severe deficiencies of growth hormone as well as of gonadotrophin and sex hormones. The literature is reviewed and the aetiology is discussed with special reference to Harris's hypothesis that an increase in growth hormone relative to oestrogen predisposes to slipping of the upper femoral epiphysis in humans, which these cases do not seem to support. In all cases the slip was bilateral, and it is emphasised that surgical treatment can provide only temporary fixation because fusion is dependent on correct hormonal therapy.

Adolescent↗