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Biomedical subjects

D L McCord

Publications and source records attributed to D L McCord.

3 recordsLinked to original sources

Radiation therapy of pure seminoma of the testicle.

An analysis of 45 patients with seminoma of the testis treated at the Radiation Oncology Department of Crawford Long Hospital of Emory University, from 1975-1986. Thirty patients with Stage I and II pure seminoma received prophylactic irradiation to the mediastinum and supraclavicular area in addition to receiving periaortic and pelvic irradiation alone. The only recurrence in the supraclavicular region was in a Stage I patient not receiving mediastinal and supraclavicular prophylaxis. No recurrences were observed in Stage II patients. The observed actuarial 5-year disease-free survival of all patients was 91.2%. In patients with Stage I disease, the actuarial 5-year survival was 93.3%. The actuarial 5 and 10-year survival of Stage II patients was 100%.

Adult↗

Isoimmunization with anti-U antibody.

Isoimmunization with anti-U antibody is a rare but significant cause of hemolytic disease in black newborns. In this case report, an lgG antibody stimulated by fetomaternal transfusion produced a positive direct Coombs' test on cord blood but not neonatal hyperbilirubinemia. A review of the literature suggests the pathophysiology is similar to Rh isoimmunization. The anti-U antibody may develop as a result of pregnancy or blood transfusion in the 1.2 percent of American blacks who are at risk for developing the antibody. The principles of treatment employed in Rh isoimmunization can be successfully used in isoimmunization due to anti-U.

Adult↗