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Biomedical subjects

D L Mollitt

Publications and source records attributed to D L Mollitt.

76 records · Page 5Linked to original sources
PubMed1978

A critical assessment of fluid requirements in gastroschisis.

This report critically evaluates the fluid requirements of 30 infants with gastroschisis. Fluid requirements were unrelated to gestational age, birth weight, or type of repair. Twenty-five percent of the fluid was colloid needed to restore intravascular volume and oncotic pressure, the balance consisting of Ringer's lactate solution. These data support the conclusion that the fluid requirements of the newborn with gastroschisis are significantly increased over those of the normal neonate. This is a reflection of antenatal peritonitis, third space fluid shifts and loss of water and electrolytes during transport to the pediatric surgical center. Recognition of these needs and appropriate replacement should reduce the perioperative morbidity and mortality in these seriously ill neonates.

Abdominal Muscles↗
PubMed1978

Mesenteric cysts in infancy and childhood.

Of 11 infants and children with mesenteric cysts, seven patients were boys and four, girls. Clinical findings included abdominal distention, pain and vomiting in seven patients, while a movable abdominal mass was noted in four. Two patients presented with peritonitis and one patient, in a state of shock. All patients underwent laparotomy-seven as an emergency procedure. Volvulus with perforation and infarction was noted in the two patients uith peritonitis. Excision of the cyst required resection of the small intestine and end-to-end anastomosis in seven patients, while simple enucleation was possible in four. All 11 patients survived, and there have been neither subsequent complications nor recurrences. Early recognition and appropriate resection of these benign, but occasionally life-threatening, malformations is associated with an excellent long term prognosis.

Adolescent↗
PubMedDate not supplied

Pediatric surgical infection and antibiotic usage.

Surgical infection is unique in that it usually requires operative intervention in conjunction with antibiotic therapy for satisfactory resolution. Prevention of infection is therefore of primary concern to the surgeon, and the majority of antibiotic use is prophylactic. Effective prophylaxis must be based on specific guidelines for patient selection and an awareness of the commonly encountered pathogens. Postoperative wound infection represents the most common surgical infection, and the clinical characteristics frequently suggest the causative bacteria. The majority of these cases respond to local wound therapy alone. Peritonitis and intraabdominal abscess are the most significant surgical infections and are almost invariably the result of intestinal contamination. Therapy must consist sequentially of resuscitation, effective antimicrobial coverage of Escherichia coli, enterococcus and Bacteroides fragiles and operative intervention.

Abdomen↗