Effect of acid etching on marginal penetration of composite resin restorations.
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Biomedical subjects
Publications and source records attributed to D L Moore.
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Entomological investigations of the possible mosquito vectors of the yellow fever epidemic on the Jos Plateau, Nigeria, were carried out between 27 October and 15 November 1969.Of the 5 species of Aedes (Stegomyia) collected, Ae. luteocephalus was the most abundant in human-bait captures. Ae. aegypti, Ae. africanus, and Ae. vittatus were collected in low numbers. The aegypti larval index in the areas investigated was very low and the species was not considered to be the primary vector in the epidemic. Ae. simpsoni larvae were abundant, but no adults were collected on human bait.Six isolates of 5 different arboviruses were obtained: yellow fever from damaged Stegomyia sp.; dengue 2 from damaged specimens, probably all Ae. luteocephalus; Zika (2 isolates) from Ae. luteocephalus; Bwamba from Anopheles funestus; and a Nyando-group virus from An. gambiae.
During an epidemic of yellow fever in the Jos Plateau area of Nigeria, 9 adult males with clinically diagnosed yellow fever were studied by haematological, biochemical, virological, serological, and liver biopsy methods. The ages of the patients ranged from 20 to 55 years and the duration of illness was 3-62 days. No virus was isolated from any patient but all patients should biochemical evidence of severe hepatocellular damage. Leucopenia was a feature of the late acute stage of the disease. Five sera had antibodies to yellow fever at titres greater than 1: 32, 3 of them being monospecific for yellow fever. The classical histological features of yellow fever were present only in the acute or late acute stages, when complement-fixation tests may be negative. With convalescence and the production of complement-fixing antibodies in high titres, the histological features resembled those of a persisting nonspecific hepatitis. In an endemic area, the histological features of yellow fever will depend on the stage of the disease and a picture of nonspecific hepatitis would not exclude yellow fever in the absence of confirmation from serological tests.