Upper extremity inhibitive casting in a boy with spastic quadriplegia.
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Biomedical subjects
D L O'Neill
Publications and source records attributed to D L O'Neill.
Active clearance of corticotropin-releasing factor from the cerebrospinal fluid.
Intracerebroventricular injection of corticotropin-releasing factor (CRF) in animals activates behavioral, motor, metabolic and sympathetic responses similar to those seen with stress. To explore the pharmacokinetics of this peptide in the primate ventricular CSF, we determined the clearance of ovine 125I-CRF from the CSF and compared it to that of 111In-DTPA, a substance cleared by bulk flow. 125I-CRF was cleared from the ventricular fluid sixfold more rapidly than bulk flow. This suggests that the CSF may be a pathway for physiological distribution of this releasing factor to active sites within the central nervous system, and that a mechanism exists for active removal of CRF from the ventricular CSF.
Animals↗
Developing goals and objectives for handicapped children.
With the enactment of Public Law 94-142, the Education for All Handicapped Children Act, public school physical therapists were mandated to participate in the development of an individual education program for each recipient of therapy services. Because each individual education program requires a statement of annual goals, including short-term instructional objectives, school therapists must become familiar with the mechanics of writing appropriate therapy goals and objectives. The purpose of this article is to present techniques for developing both annual therapy goals and short-term, behaviorally written treatment objectives. The components of a behavioral objective are specified, and good and bad examples of pediatric therapy objectives are shown. The importance of collecting data to measure progress toward the achievement of short-term objectives is also discussed.
Child↗