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Biomedical subjects

D L Solanki

Publications and source records attributed to D L Solanki.

5 recordsLinked to original sources

Severe mycoplasma pneumonia with pleural effusions in a patient with sickle cell-hemoglobin C(SC) disease. Case report and review of the literature.

We describe a patient with sickle cell hemoglobin C(SC) disease in whom severe pneumonia developed complicated by large bilateral pleural effusions and respiratory failure. Mycoplasma infection was not initially suspected but was subsequently proved serologically. The course of the illness was unusually long. A review of the literature showed occurrence of large pleural effusions to be infrequent for pulmonary infection with Mycoplasma in adults, with only eight such cases previously reported. The possibility of Mycoplasma pneumonia should not be dismissed merely because of the severity of the illness or the presence of pleural effusions.

Adolescent

Fragmentation hemolysis in idiopathic hypertrophic subaortic stenosis.

A 69-year-old woman with previously asymptomatic IHSS developed fragmentation hemolytic anemia in association with bacterial endocarditis when the calculated pressure gradient across the left ventricular outflow tract was 82 mm Hg. Partial correction of the anemia by transfusion resulted in a prompt reduction in fragmentation. The interplay of anemia and increased pressure gradient in the production of red cell fragmentation is discussed.

Aged

Cholelithiasis in sickle cell anemia: a case for elective cholecystectomy.

Ten patients with sickle cell anemia over the age of 10 who had cholecystectomy are reported. All had symptomatic cholecystitis; three had biliary tract obstruction. Transfusions were given preoperatively and with attention to oxygenation and fluid and electrolyte balance. There were few complications, none serious. Based upon the frequency of gallstones over the age of 10, the likelihood of symptoms or serious complications and the apparent ease with which the properly prepared sickle cell patient comes through surgery, we recommend routine cholecystograms in all adolescent and adult sickle cell anemia patients with elective cholecystectomy for those who have stones.

Adult