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Biomedical subjects

D L Weber

Publications and source records attributed to D L Weber.

At least 19 recordsLinked to original sources

Detection and recognition of repeated tones and tonal patterns.

This study examined the effect of multiple presentations on signal detection and on signal recognition (identifying one signal from a set of four possible signals) for three different sets of signals. One set was four sinusoids (100-ms duration, frequencies of 707, 1000, 1414, and 2000 Hz). Two sets contained tonal patterns each made of a sequence of seven, 100-ms, sinusoidal components. In the first set, the four patterns consisted of the same seven sinusoids in different orders. In the second set, the four patterns had the same order of relative frequencies, but had frequencies from different 1/4 oct bands centered at 707, 1000, 1414, and 2000 Hz. All stimuli were adjusted to be equally detectable in the presence of a continuous white noise (eta 0 = 20 dB SPL). Each trial contained 1, 2, 4, 8, or 16 presentations of a given signal plus noise (probability of a signal was 0.5) or noise alone. Detectability of the sinusoids generally increased as the square root of the number of presentations; detectability for the tonal patterns increased at a slower rate. Recognition was generally poorer than predicted by the recognition theorem [S.J. Starr, C. E. Metz, L.B. Lusted, and D.J. Goodenough, Radiology 116, 533-538 (1975)] and increased with multiple presentations only as much as expected from the increase in signal detectability.

Acoustic Stimulation

Abnormal stimulus processing in posttraumatic stress disorder.

This study investigated event-related potential (ERP) indices of information processing in sufferers of posttraumatic stress disorder (PTSD). ERPs were obtained from 18 PTSD patients and 20 controls while they performed a target discrimination task requiring the detection of infrequent target tones from a background sequence of frequent and infrequent distractor tones. A delayed N2 and an attenuated P3 that failed to differentiate target from distractor tones indicated that patients had abnormal difficulty distinguishing task stimuli of differing relevance. It is proposed that this difficulty is reflected behaviorally in the slowed reaction time by patients to target stimuli and may underlie the disturbed concentration and memory impairments found in PTSD. It may also be related to dysfunction in central noradrenaline function, which has been shown to be both crucial in selective attention and abnormal in PTSD.

Adult

Detection and recognition of auditory patterns.

The detection/recognition theorem (Starr, Metz, Lusted, & Goodenough, 1975) provides a signal detection theory prediction of an observer's ability to identify one of a set of possible signals on the basis of the observer's ability to detect whether any signal is presented. The present findings show that the theorem can be applied to complex auditory stimuli in a fashion that is not merely a trivial extension of the results obtained with simple auditory stimuli.

Adult

Procedure-independent growth-of-masking functions.

The forward-masked threshold for a 10-ms, 1-kHz sinusoidal signal was measured as a function of the level of a narrow-band (60-Hz wide) noise masker at five masker frequencies (0.6, 0.8, 1.0, 1.15, and 1.25 kHz) using both a fixed-masker procedure (determine the threshold level of the signal for a fixed level of the masker) and the converse procedure (determine the masker level necessary to just mask a given signal). A common growth-of-masking function describes the results of both procedures for a given masker frequency; i.e., an identical masker and signal lead to identical performance regardless of which is the dependent variable. The growth-of-masking functions for different masker frequencies show varying degrees of nonlinearity. The nonlinearity of the growth-of-masking functions underlies the discrepancies which arise between masking-pattern and tuning-curve data. These discrepancies do not arise because performance somehow depends upon whether the masker or signal is the dependent variable.

Acoustic Stimulation

Sinusoidal and noise maskers in simultaneous and forward masking.

We compare psychophysical tuning curves obtained with sinusoidal and narrow-band (50-Hz wide) noise maskers in both simultaneous and forward masking. In one experiment, we examine the effects of different combinations of duration and intensity of the 1-kHz sinusoidal signal. In a second experiment, we compare tuning curves obtained with a sinusoidal signal to those obtained with a noise signal. In both experiments, a narrow-band noise is a more effective simultaneous masker than a sinusoid for masker frequencies near the signal frequency. We argue that this is probably due to the use of different detection cues in the presence of sinusoidal and noise maskers, and that the greater masking produced by the noise is not simply due to its greater variability. As observed in other studies, tuning curves are narrower in forward masking than in simultaneous masking.

Auditory Perception

Combined effect of two suppressors.

Threshold for a 10-ms sinusoidal signal was measured as a function of signal frequency (0.65 to 1.40 kHz) in several forward-masking conditions. For signal frequencies near 1.0 kHz, the forward masking produced by a 395-ms, 100-Hz-wide noise centered at 1.0 kHz (total power 60 dB) could be reduced by the addition of a sinusoid to the noise. The effects of four sinusoidal suppressors (frequencies of 0.70, 0.85, 1.15, and 1.40 kHz, all at 75 dB SPL) were examined individually and in the six possible pairwise combinations. In general, the threshold reduction produced by two suppressors together was no greater than the larger of the reductions produced by the suppressors individually. It appears that suppression produced by different stimuli does not combine to yield significantly larger effects. Instead, the amount of suppression appears to be restricted to a specific range and it is not possible to exceed this limit.

Acoustic Stimulation

Relation between cubic-difference-tone generation and suppression.

Two aspects of the relation between cubic-difference-tone (CDT) generation and suppression were investigated in normal hearing listeners. First, the effects of narrow-band noise and sinusoids on the two processes were examined using a forward-masking paradigm. Within individual listeners, cubic difference bands (CDBs) behaved much like CDTs whereas the suppression effects produced by narrow-band noise were substantially less than those produced by sinusoids. These results suggest that at least partially different processes underlie the two the two phenomena. Second, the role of suppression in the difference between forward- and simultaneous-masking estimates of CDB amplitude was investigated. The data across listeners were highly variable but indicated a more complicated interpretation than that proposed by Shannon and Houtgast [J. Acoust. Soc. Am. 68, 825-829 (1980)].

Acoustic Stimulation

Do off-frequency simultaneous maskers suppress the signal?

Psychophysical tuning curves obtained in forward masking show greater tuning than those obtained in simultaneous masking. This difference is often attributed to the contribution of suppression to the masking produced by off-frequency simultaneous maskers. In this experiment, simultaneous-masking tuning curves were obtained using a 195-ms, 1-kHz sinusoidal signal presented at 40 dB SPL. If the maskers identified in this procedure reduce signal detectability by suppressing the response to the signal, then it should be possible to demonstrate suppression effects between stimuli with the parameters of the masker and signal. One conventional method for demonstrating suppression is to show a reduction in the amount of forward masking produced by one stimulus when a second stimulus is added to it. When used to test the effect of the masker upon the signal, this procedure does not show the suppression supposedly produced by the off-frequency maskers. These data are consistent with an alternative explanation involving only excitatory interactions between masker and signal.

Adult

Ten central elements of family practice.

Previous studies of the content of family practice have analyzed the discipline in terms of the clinical problem content. Taking a different approach, a study group analyzed the care given to patients by family physicians irrespective of the specific clinical problems. Working with a reference group of family physicians in private practice, ten central elements were identified: (1) comprehensiveness of care, (2) anticipation of problems and continuity of care, (3) personal relationships with a patient, (4) medical knowledge and skills characteristic of family medicine, (5) values and attitudes that enhance family medicine, (6) problem definition and medical decision making, (7) problem management and resource coordination, (8) care of the individual within the family context, (9) involvement with the community, and (10) attentiveness to practice organization. This study provides a different point of departure for the design and evaluation of educational programs in family practice.

Adult

The deterioration of hearing with age: frequency selectivity, the critical ratio, the audiogram, and speech threshold.

The frequency selectivity of the auditory system was measured by masking a sinusoidal signal (0.5, 2.0, or 4.0 kHz) or a filtered-speech signal with a wideband noise having a notch, or stopband, centered on the signal. As the notch was widened performance improved for both types of signal but the rate of improvement decreased as the age of the 16 listeners increased from 23 to 75 years, indicating a loss in frequency selectivity with age. Auditory filter shapes derived from the tone-in-noise data show (a) that the passband of the filter broadens progressively with age, and (b) that the dynamic range of the filter ages like the audiogram. That is, the range changes little with age before 55, but beyond this point there is an accelerating rate of loss. The speech experiment shows comparable but smaller effects. The filter-width measurements show that the critical ratio is a poor estimator of frequency selectivity because it confounds the tuning of the system with the efficiency of the signal-detection and speech-processing mechanisms that follow the filter. An alternative, one-point measure of frequency selectivity, which is both sensitive and reliable, is developed via the filter-shape model of masking.

Adult

Forward masking by sinusoidal and noise maskers.

A 2-kHz sinusoid and a narrow-band noise centered at 2 kHz, with the same total power, served as maskers for a 2-kHz sinusoidal signal. We compare the forward masking produced by these two maskers (1) as a function of offset--offset time for 5- and 35-ms signals, (2) as a function of signal duration for a fixed offset--onset time, and (3) as a function of signal duration for a fixed offset--offset time. In all these comparisons, we find that the noise and sinusoid not only produce different amounts of masking for the same experimental condition, but they also show different trends for the same manipulation. The important relations in these results are demonstrated in an additional set of conditions with a 1-kHz signal. In order to account for the differences observed in both experiments, we argue that forward masking is determined by at least two factors. We suggest signal energy as one factor and the presence or absence of differences in quality between masker and signal as another.

Audiometry

Detection of temporally uncertain signals.

The effects of signal uncertainty on detection performance were measured using a new procedure that allows precise specification of the initial temporal uncertainty. Five different models of the detection process, two assuming a continous representation of the sensory input and three assuming a discrete representation, were compared with the obtained data. The effects of varying signal uncertainty (the number of potential signal intervals was one, five, or ten) had little effect on detection performance. The one-parameter form of the choice model can be rejected without hesitation. The continuous Gaussian model and the symmetric two-state model are significantly different from the data. The high threshold and sophisticated two-state models provide accurate descriptions of the data that cannot be rejected on statistical grounds.

Acoustic Stimulation

Suppression effects in backward and forward masking.

The differences in the suppression effect observed in forward and backward masking are consistent with an interpretation that suppression in forward masking results from a reduction of the effective level of the masker in the aditory periphery, and that the suppression in backward masking is influenced by these peripheral processes, but is dominated by additional, central processes. This conclusion is supported by experiments that show differences in the effect of ipsilateral versus contralateral presentation of the suppressor, and differences in the amount of the suppression observed as a function of the level, duration, and frequency of the suppressor.

Adult

Suppression and critical bands in band-limiting experiments.

Band-limiting experiments were performed at three noise spectrum levels (N0 = 25, 40, and 55 dB SPL) for forward, simultaneous, and backward masking. Threshold for a 2-kHz sinusoid decreased for masker bandwidths greater than a "critical bandwidth" in nonsimultaneous masking. These results are evidence for a suppression effect not observed in simultaneous masking; however, a qualitative model of suppression can account for the results in all three types of masking. In addition, the data for simultaneous masking support Fletcher's [Rev. Mod. Phys. 12, 47--61 (1940)] rectangular filter interpretation of the band-limiting experiment and are well described by a level-dependent critical band.

Auditory Threshold

Temporal factors and suppression effects in backward and forward masking.

We discuss several experiments examining the influence of temporal parameters on suppression effects in backward and forward masking. The signal is always a brief 10-ms 2-kHz sinusoid; the masker a narrow band of noise of 40-dB spectrum level, 200-Hz wide, centered at the signal frequency. In some conditions, the presence of a second band of noise of the same spectral level in the region of 2300--3700 Hz appears to suppress the effects of the masker. Changes in the amount of suppression are examined as functions of the delay and duration of the suppressor (experiments 1 and 2). Adding the suppressor during the 50-ms interval nearest the signal produces changes in the signal threshold that are similar to those produced by reducing the level of the masker during this interval for both backward and forward masking (experiment 4). The similarity of these results suggests the operation of peripheral processes common to both backward and forward masking. However, if one increases the duration of the suppressor beyond this 50-ms interval there is no effect on forward masking, but large additional reductions in backward masking. This difference, in conjunction with other recent experiments, suggests the operation of additional central processes in backward masking. For some observers, these additional processes appear to operate over fairly long periods of time (250-500 ms). Such long durations are inconsistent with the estimates of integration time (less than or equal to 200 ms) obtained for these same observers (experiment 3).

Adult

Detection and recognition of pure tones in noise.

We examine the predictions of a new theorem relating signal identification (specifying a signal as a particular member of a set of potential signals) to signal detection (discriminating the presence of a signal). The theorem, derived in the context of signal-detection theory, requires that the signals be equally detectable and orthogonal. Our sinusoidal signals are partially masked by noise and their intensities adjusted to produce equal-signal detectability; we do not examine this assumption of the theorem. The theorem generally provides a reasonably accurate description of recognition performance for two-signal and four-signal conditions and is equally accurate for both the Yes-No and category-rating procedures. In a preliminary investigation of the orthogonality assumption, we varied the frequency separation between two signals. When the frequency separation between two signals is small (20 Hz near 1 kHz), the theorem fails to provide a good description of performance.

Humans