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Biomedical subjects

D Labayle

Publications and source records attributed to D Labayle.

At least 73 records · Page 4Linked to original sources
PubMed1977

[Hepatology in 1977].

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Chemical and Drug Induced Liver Injury↗
PubMed1976

[Rheumatoid polyarthritis: should corticotherapy be interrupted in case of gastro-duodenal ulcer?].

The possibility of healing of a corticosteroid-induced ulcer depsite the continuation of the treatment, is now an established fact. It is thus reasonable to continue corticosteroids in those cases where interupption severely compromises the prognosis. The chances of healing of the ulcer would appear to be great, especially when corticosteroids are being used in low dosage, but the exact frequency of healing remains unknown, just as the frequency of ulcers due to corticosteroid therapy has not been accurately established.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Homogeneity of the erythrocyte volume distribution during chronic alcoholism macrocytosis (author's transl)].

The increase in volume of human erythrocytes during chronic alcoholic intoxication and its decrease after alcoholic deprivation was studied with a multichannel analyzer. When fractions of the population of red cells were separated by differential centrifugation the macrocytosis was found to be uniformly distributed. The presence of macrocytes was not related to changes of plasma osmolality or hyperhydration of red cells. A central origin was evoked, however, the role of the folic acid deficiency could not explain the macrocytosis, the mechanism of which remains to be elucidated.

Adult↗
PubMedDate not supplied

[Candidiasis involvement of the small intestine complicated by perforation. A case of favorable course].

We report the case of a 51 year-old man who developed candidiasis of the small bowel associated with intestinal perforation. This condition is very rarely recognized ante mortem. Here, the diagnosis was established by pathological examination of a surgically resected specimen of small bowel at the time of surgery. A complete work-up failed to disclose any predisposing condition to digestive candidiasis. Antifungal therapy resulted in complete recovery.

Candidiasis↗
PubMedDate not supplied

[Metabolism and kinetics of ampicillin elimination in cirrhosis. Therapeutical consequences (author's transl)].

In cirrhotic patients, the authors studied the modification of the pharmacokinetics of ampicillin in the plasma and in the ascitic fluid, as well as its concentration in the urine. The influence of the jaundice, the ascites and diuretics were studied. In cirrhosis, dilution and elimination of the antibiotic are modified, as is shown by the increase in T 1/2 alpha and T 1/2 beta. These anomalies seem to be due essentially to modifications in the distribution volume; the degree of hepatocellular insufficiency does not appear to be of importance. The ascites acts as an independent compartment, into which the antibiotic's passage is slight. The practical consequences are the following: less frequent injections, increasing of the fractionated doses, in situ injections of ampicillin in cases of infection of the ascitic liquid.

Ampicillin↗