[Hemoglobin synthesis in acute leukemia and refractory anemia].
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Biomedical subjects
Publications and source records attributed to D Labie.
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HbA1c percentage was determined in 82 insulin-dependent juvenile diabetic patients. The concentration of HbA1c reflects the level of chronic hyperglycaemia during the preceding 4 to 8 weeks and appears to correlate closely with the commonly used methods for monitoring diabetic control. HbA1c measurement provides a reliable and objective test for periodic assessment of insulin-dependent juvenile diabetes. It may serve as a valuable tool for determining the level of metabolic control in each patient and measuring the effectiveness of various therapeutic regimens.
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We have studied haemoglobin (Hb) variants and blood groups (ABO, RH, and Kell) in 598 children from the Berber population of the Mzab. Hb D-Ouled Rabah, considered as a private marker of the Kel Kummer Tuaregs, and Hb C were found at the same gene frequency (0.015). Haplotype analysis suggests a single origin to the Hb D mutation. Genetic distances calculated from the blood group data cluster Mozabites and Tuaregs with the other Berber-speaking groups, Arabic-speaking populations being more distant. But, we found no specific relationship between Mozabites and Kel Kummers. Tuaregs in general exhibit features that tend to differentiate them from other Berber-speaking groups. Hb D-Ouled Rabah may be specific of Berber-speaking populations.