Neonatal intestinal ischemia with bowel perforation: an in utero complication of maternal cocaine abuse.
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Biomedical subjects
Publications and source records attributed to D Lewin.
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Uterine inversion is exceptional and spectacular, although treatment is simple if diagnosed early. Three cases are reported with a review of possible obstetrical procedures for reduction. Manual repositioning by central pressure is emphasised. General anesthesia is generally needed because of associated state of shock. The three principal steps of manual reduction are: intra-abdominal repositioning of the uterus, removal of placenta, intramural injection of ocytocine to avoid immediate relapse. Ideally, obstetrical procedure should be carried out within one-half hour after inversion.
The authors report a case of two siblings who developed a neonatal alloimmune thrombocytopenia (NAITP) due to Bak-System incompatibility. They review the platelet antigen systems involved in NAITP and raise the problem of its present antenatal and postnatal management.
A case of congenital chylothorax diagnosed with prenatal ultrasonography is described. Thoracocentesis was performed at 33 weeks of gestational age but recurrence of chylothorax, increasing hydramnios and subcutaneous oedema made cesarean section necessary at 37 weeks. Mechanisms of chylothorax during the fetal life and its management before and after delivery are discussed.
This paper presents some results on the range of clinical responsibilities undertaken by three cohorts of student nurses in basic training. It concentrates on the quantity and variety of a student's clinical experience. Seventy-seven important items in nurse training, classified into three groups (general nursing, responsibility situations and interpersonal situations) are discussed.
Two groups of women who had labours induced were compared in a prospective randomised trial: The first group of 41 patients (group 1) in whom the epidural was started at the beginning of induction. A second group of 47 patients (group 2) in whom the epidural was only started when labour became "active" and induction had been effective. The length of labour and the obstetrical results were identically the same in both groups: at least there was no significant difference. There was no special benefit from waiting until labour started properly before injecting the epidural. This result made us look retrospectively to women whose labours had been induced and who might have benefited from the epidural being started late. The only significant difference was found apparently between primipara and multipara, and this was quite independent of the state of the cervix and the lower segment at the onset: it would appear to be better to put the epidural analgesia in once the labour has started in primiparous patients where as in multiparous ones on the other hand there seems to be a better effect if the epidural is started as soon as induction is started.
The author presents his views on the advantage of a large database in obstetrics. The objectives and methods, as well as the main previously encountered difficulties, are analyzed.
During pregnancy, the opening of the cervix can be measured by perineal echotomography. Among 200 per-gravidic clinical echotomographies, 23 cervical incompetences were recognized. A "funnel-shaped" cervix is a cervix with an internal os larger than the external os; thus no clinical sign may be apparent and only a supra-vaginal Shirodkar's operation should be done.
An open-end catheter and a small strain gauge were tied and introduced into the uterine fundus during the labor of 8 parturients. As the tied probes were progressively withdrawn, the pressures given by each were simultaneously recorded. Normally the measurements are identical, but when the free ends of the probes are located between the head and the cervix, striking differences appear, the strain gauge giving much higher figures. Conversely, two intrauterine open-end catheters give the same results even if one is located in the fundus and the other is between the head and the cervix. It is suggested that the strain gauge measures a pressure which is not reliable enough because the area of application of the stress cannot be known accurately.
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We have been able to show that fetal cells are able to survive and multiply in the haematopoietic organs of the pregnant mouse. We have been able to label fetal cells with a chromosome marker (T6) which is clearly visible in the metaphase of mitosis. It is not only that there is a considerable concentration of fetal cells in the maternal spleen (3 to 6 per cent) but there are several factors that suggest that these fetal cells can multiply there. These are, the presence of mitoses, long survival, and a rise in numbers in the case of a new pregnancy. Thus pregnancy seems to bring about a physiological "microchimerism".
The authors have previously described a method of objectively assessing the height of the presentation, an ultrasonic echograph measuring the distance from the head to the sacral tip. They have now obtained 453 measurements made before and during labor; norms are given according to the clinical evaluation of the station. The usefulness of the method is discussed. It may make the Bishop's score more precise, permit a more accurate check of trial of labor and help to recognize a low station correctly before an application of forceps.
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The uterus can contract without innervation and without nodal tissue. On the model proposed, purely myogenic regulation results from certain properties of the elementary contractile units of the uterus. Using a fragment of a tracing of the intrauterine pressure curve, the theoretical continuation of such a tracing can be calculated.
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