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Biomedical subjects

D Light

Publications and source records attributed to D Light.

32 records · Page 2Linked to original sources
PubMed1986

The effect of the surface finish of alumina and stainless steel on the wear rate of UHMW polyethylene.

The effect of the surface finish of medical grade alumina and stainless steel on the wear rate of ultra-high molecular weight (UHMW) polyethylene was studied in a six station pin-on-plate wear screening device using bovine serum as lubricant. The wear rate decreased as the surface finish of alumina improved from 0.10 to 0.015 micron Ra, with no evidence of an increasing wear rate below a particular value of surface finish. Tests with surgical grade stainless steel showed a similar polyethylene wear rate around the 0.025 micron Ra level, but there was evidence of a higher wear rate with stainless steel than with alumina between approx. 0.035 and 0.075 micron Ra.

Aluminum↗
PubMed1986

Laplace's law.

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Colon↗
PubMed1985

A comparison of RCH 1000 and Hi-Fax 1900 ultra-high molecular weight polyethylenes.

Hoechst RCH 1000 and Hercules Hi-Fax 1900 ultra-high molecular weight (UHMW) polyethylenes have been compared, for the first time, in tests, including wear, fatigue and creep, relevant to artificial human joints. In none of the tests was the behaviour of the Hercules material inferior to that of RCH 1000, and in the wear and creep tests it was superior.

Animals↗
PubMed1985

Delayed pulmonary maturation in the fetus of the streptozotocin-diabetic rat.

Pulmonary maturation was studied in fetuses in streptozotocin-diabetic rats on the final four days of gestation. Diabetes was induced prior to conception by the intravenous injection of streptozotocin. Fetuses were hyperglycemic but did not manifest hyperinsulinemia. Whole lung total phospholipid, phosphatidylcholine, and disaturated phosphatidylcholine were significantly decreased in the diabetic group on day 21 (term = 22 days), but not prior to or after that point in gestation. Morphologic analysis also revealed a decreased number of type II cells and lamellar bodies per alveolar lining cell in the diabetic group only on day 21, coincident with the changes in phospholipid analysis. Activities of enzymes involved in fetal pulmonary phospholipid synthesis were measured to see if differences could account for the observed developmental delay. No significant differences between diabetic and control lungs were noted in any of the enzymes studied from days 20-22, with the exception of an increase in cholinephosphate cytidylyltransferase activity in the diabetic fetuses on day 22. Immaturity in both biochemical and morphologic indices of lung development was present at a specific time late in the diabetic rat gestation. This maturational delay could not be accounted for by changes in the activities of enzymes involved in phospholipid synthesis. The fetus of the streptozotocin-diabetic rat provides a useful model to study the effects of hyperglycemia on fetal lung development.

Animals↗
PubMed1985

Characteristics of primary isolates of alveolar type II cells from neonatal rats.

Alveolar type II cells from 6-day-old rat pups were obtained at approximately 90% purity, as judged by light and electron microscopy. Within 48-72 h in culture, the cells formed a monolayer with tight junctions typical of epithelial cells. Type II cells aggregated into raised domelike areas, which when sectioned showed alveolarlike structures comprised of type II cells. After 3 days in culture these structures showed abundant lamellar body secretion. Phospholipid profiles were characteristic of type II cells, with disaturated phosphatidylcholine (DSPC) the predominant secreted phospholipid. The cells also released DSPC in response to beta-adrenergic stimulation. This release was inhibited by the specific beta-antagonist propranolol. The results show that morphologic differentiation and biochemical properties of neonatal type II cells can be studied using an isolated cell system in tissue culture.

Animals↗
PubMed1983

The laboratory development of a new metacarpophalangeal prosthesis.

The paper describes the design and laboratory testing of a new metacarpophalangeal prosthesis. The novel features of the new design include the joining of pairs of prostheses by common hinge-pins and the inclusion of bearings within the proximal phalanges. The common hinge-pins are designed to prevent the recurrence of ulnar drift by sharing the forces on one finger with a neighbouring joint, and together with the intramedullary bearings to prevent potentially loosening torques from acting on the fixation of the components.

Biomechanical Phenomena↗
PubMed1977

Beef cattle productivity under traditional and improved management in Botswana.

A comparison of productivity over a 4-year period from indigenous type beef cattle under two production systems in Botswana is reported. The two systems are: the traditional system on unenclosed communal grazing (cattle post) and ranching within fenced paddocks. Calving percentages, 7-month old calf weight, calf mortality and post-weaning growth to 18 months of age under cattle post conditions were 46.4 per cent, 122.5 kg, 10.2 percent and 88.5 kg respectively. Corresponding figures for cattle on the fenced ranches were 74.0 per cent, 177.4 kg, 8.5 per cent and 105.8 kg. These results indicate overall productivity estimates of 51 and 120 kg of weaner calf per cow per year and 86 and 188 kg of 18-month old calf per cow per year for the cattle post and fenced ranch respectively.

Animal Husbandry↗
PubMed1975

The impact of medical school on future psychiatrists.

Although psychiatry and clinical medicine share ideals about what distinguishes a good practitioner, medical schools do not select students on the basis of these qualities. Moreover, they seem to discourage many interested students from choosing psychiatry. Part of the problem is that psychiatry is poorly taught. Research suggests that psychiatry can be better taught and that medical students will be receptive. However, the clash between the values of technological medicine and psychiatry has created discouragement, with the ironic result that medical students rate psychiatrists poorly because they embody the very qualities that distinguish the good clinician.

Attitude of Health Personnel↗
PubMedDate not supplied

Saving John Worthy.

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Humans↗