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Biomedical subjects

D Louis

Publications and source records attributed to D Louis.

At least 73 records · Page 4Linked to original sources

[Digestive stenosis after neonatal enterocolitis].

Nineteen clinical cases of intestinal stricture due to neonatal necrotising enterocolitis and a review of available references are presented in this paper. Intestinal strictures are estimated to arise in 20% to 30% on neonatal enterocolitis. However the delay between the acute episode and the occurrence of the stenosis is variable; the depth and the extend, of the necrosis as well as inflammation and superinfection may contribute to the building up of the intestinal stricture. The histological aspects of the lesions are not unique, more over cases of spontaneously regressive stenosis are known. Question thus arising as to the most appropriate timing for surgery and the choice of surgical technics as a function of clinical aspects and of derivation of the disease are discussed in this paper.

Colonic Diseases↗

Physiologic investigation of primary chronic constipation in children: comparison with the barium enema study.

Rectoanal manometry and a rectometrographic study were carried out on 31 control subjects and 63 constipated children. A single contrast barium enema was performed on all constipated children and on 20 children for whom this x-ray study (made for a reason other than constipation) was considered normal. This study allowed the determining of four manometric parameters (rectoanal inhibitory reflex threshold, rectorectal reflex threshold, conscious rectal sensitivity threshold, maximal anal resting closure pressure), of three rectometrographic parameters (maximal rectal tolerable pressure, maximal rectal tolerable volume, maximal rectal compliance), and of one radiologic parameter (rectopelvic ratio). It appeared that the barium enema study was not meaningful. The threshold of the inhibitory reflex and of the rectoanal reflex did not allow for a specific definition of abnormality in constipation. Anal closure pressure was higher in 38% of the constipated patients. The sensitivity threshold was significantly higher in the constipated group. In 79% of the patients an increase in rectal compliance was observed. Finally, in this series of constipated patients who did not have Hirschsprung's disease, organic abnormalities were demonstrated in 97% of the children.

Adolescent↗

[Obstruction due to congenital tracheal and bronchial stenosis].

Report of seven cases of congenital tracheal and bronchial stenosis in infants, successfully treated by endo-resection (2 cases), tracheoplasty (1 case) and resection with anastomosis (4 cases). The review of several cases of literature let to emphasize some points: the frequency of severe manifestations since neonatal period and during the first months leading to repeated hospitalisations with the treatening of broncho-pulmonar infections; the necessity of early diagnosis and complete anatomic evaluation of stenosis, which sometimes requires to be promptly treated in front of a sudden recurrence of respiratory distress; at last, improvements of reconstructive surgical technique, tracheoplasty for diffuse stenosis, endo-resection or resection with anastomosis for segmental lesions, which the results point out the possibilities and indications of that surgery in the infants.

Abnormalities, Multiple↗

[Impact of reflux on the kidney].

Description of the reflux nephropathy. Pyelonephritis lesions are undoubtedly linked to the vesico-ureteric reflux. The role of the intra-renal reflux ( Hodson ) and the Big Bang Theory ( Ransley ) are discussed as the data from animal experiments. The role of the sterile reflux and of the segmental hypoplasia is relatively less important. The actual management of vesico-ureteric reflux treatment is questioned.

Child↗

[Azygo-portal disconnection using the thoracic approach in children].

Porto-azygos disconnection is one of the therapeutic choice of portal hypertension. This technique have been used in a 13 year old boy with bleeding oesophageal varices during the evolution of a cirrhosis caused by active hepatitis. Disconnection was done in emergency using a total ligature of the oesophagus by left thoracotomy upon a clip introduced by oral way. By this technique, the abdomen and the digestive tract keep untouched. One year after the operation no oesophageal varices can be seen at endoscopy and a slight oesophageal stenosis have been easily treated by dilatations.

Adolescent↗

[Enlarged substitutive colocystoplasty for congenital neurological bladder in children. Apropos of 8 cases].

The encouraging success of replacement of the detrusor for contracted bladder due to a tuberculosis or other causes prompted an attempt to reconstruct bladder in a patient with neuropathic bladder. Colocystoplasty has been used by the authors in a total of 12 children with neurogenic bladder: 8 with a sufficient follow-up (6 months to 10 years). Technical data are given with some details. The sclerosed detrusor inducing elevated bladder pressure must be resected and the sigmoid is anastomosed to the trigone of the bladder. The sigmoid conduit is extraperitonized. The new colonic bladder give ample and supply cystern allowing protection of ureters and kidneys. The incontinence is not modified. Simultaneously with colocystoplasty the patient must be managed by self-catheterization or by urinary artificial sphincter or by a continent cystostomy. The initial results are very encouraging.

Adolescent↗