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Biomedical subjects

D Lyonnet

Publications and source records attributed to D Lyonnet.

52 records · Page 3Linked to original sources

[The use of simultaneous angiography to determine the signification of vascular images in renal scintiscans with technetium (author's transl)].

Combined angiography and renal scintiscans were used by the authors in an attempt to determine the signification of the images and vascular tracings obtained after intravenous injection of technetium (99mTc). They conclude that the scintiscan images are essentially the reflection of cortical vascularization and that its duration, as determined by the scintiscan, is roughly equal to the mean transit time of the indicator employed (Tc). Arterial stenosis cannot be demonstrated by scintiscans using technetium.

Adolescent↗

Renal microvasculature following papillary resection.

Surgical papillectomy was performed on 39 rabbits. Microvasculature initially remained normal. After cortical fibrosis occurred, a diversion of the blood flow from the cortex to the medulla was noted. Cortical atrophy following papillary loss is not secondary to microvasculature insufficiency, but is a consequence of obstruction of the collecting ducts. The physiologic changes which follow papillectomy are due to interruption of the loops of Henle and cortical scarring.

Animals↗

Regional blood flow to the lymph node during the immune response.

In 62 New Zealand white rabbits the regional blood flow to the popliteal lymph node was determined using the microsphere distribution and the Rb86C1 indicator methods. In 20 animals local immune response was induced with typhoid O antigen and in 7 with bovine serum albumin. The regional blood flow of the popliteal lymph node was 0.57 ml/gm/min. During the immune response the blood flow and weight changes were strictly proportional. The lymph node has the capacity to maintain its blood flow, even following significant enlargement.

Animals↗

A comparison of the efficacy and safety of ioxaglate and iobitridol in renal angioplasty.

PURPOSE: To compare ioxaglate and iobitridol for percutaneous transluminal renal angioplasty (PTRA) as regards thromboembolic complications, the quality of diagnosis, and renal and general safety. METHODS: One hundred and eighty-nine patients were prospectively studied, 98 of whom received ioxaglate, and 91, iobitridol. Twenty-two were secondarily excluded from the evaluation of thromboembolic complications as they did not undergo PTRA. RESULTS: Two hundred and two PTRAs were performed. The total volumes of contrast medium administered and the procedure durations were the same for each patient. In the ioxaglate group, four dissections (3 stents), one occlusive dissection, and two spasms occurred; in the iobitridol group, there were three dissections (all stented), one occlusive dissection (stented), and two spasms. The final angiograms showed four renal infarctions with ioxaglate (2 of which were in patients who were not anticoagulated), two with iobitridol. No significant difference was seen in the incidence of thromboembolic complications when the PTRA was performed after anticoagulation (n = 150; 3.9% vs 4%, p = 0.78); in the whole population, thromboembolic complications were more frequent in the ioxaglate group but the difference was not significant (5.7% vs 3.7%, p = 0.74). The quality of the diagnosis and the general and renal safety were the same in the two groups. CONCLUSION: Regarding the clotting phenomenon, we recorded as many thromboembolic complications with ioxaglate as with iobitridol.

Angioplasty, Balloon, Coronary↗

[Transthoracic puncture and excavated pulmonary lesion. Diagnostic contribution and value of the extemporaneous cytologic test].

Twenty-six cases of excavated pulmonary masses are reported. In 18 cases malignancy was proven by transparietal needle aspiration. A false-negative result was due to the needle being introduced too centrally and bringing pus, whereas the tumour was an epidermoid carcinoma. The seven non-malignant lesions consisted of abscess in 4 cases, tuberculosis in 1 case and pulmonary embolism in 2 cases. The sensitivity and specificity of the technique were similar to those observed in large series of transparietal needle aspiration of solid masses. Using thin needles and extemporaneous cytology reduced the number of complications: haemothorax 6 percent, haemoptysis 0.4 percent. The authors conclude that in excavated pulmonary masses transparietal needle aspiration provides a diagnosis of malignancy when the radiological and clinical courses and bronchial fibroscopy are inconclusive. Transparietal needle aspiration avoids the need for other investigations, such as exploratory thoracotomy, thereby reducing the cost of diagnosis.

Aged↗

[Magnetic resonance imaging in the evaluation of malignant melanoma of the choroid and ciliary body].

We evaluated 16 patients with malignant melanomas of the choroid (11) or the ciliary body (5) by magnetic resonance imaging (MRI), using a 0.5 T magnet and a surface coil. The tumor was seen in all cases, hyperintense in T1-weighted images, and hypointense in T2-weighted sequences (80%). These images reflected the short T1 and T2 relaxation times caused by the presence of melanin in those tumors. This non-invasive method was superior to computed tomography (70%), and sometimes superior to fundoscopy (2 cases), angiofluorography (3 cases) or echography (1 case). MRI also proved valuable for differentiating uveal melanoma from associated subretinal effusion.

Adult↗