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D M Balfe

Publications and source records attributed to D M Balfe.

112 records · Page 7Linked to original sources

Computed tomography of portal vein thrombosis: unusual appearances and pitfalls in diagnosis.

In a review of 25 cases examined by CT in whom the diagnosis of visceral vein thrombosis had been made, we encountered four cases in which problematic CT findings led to an error in diagnosis by the prospective interpreter. In one case, gas in collateral periportal veins mimicked an abscess; in one case, segmentally occluded portal veins resembled dilated bile ducts; and in one case, expansion of the inferior mesenteric vein was interpreted as a pancreatic pseudocyst. One additional case of multiple intrahepatic stones mimicked calcified portal vein thrombus. Although most cases are straightforward, there is a spectrum of findings in visceral vein thrombosis that may lead to confusion; alternative imaging techniques may be necessary in these situations.

Adult↗

"Acute" fat deposition in bowel wall submucosa: CT appearance.

OBJECTIVE: The deposition of submucosal fat in small and large bowel is known to occur in chronic processes such as inflammatory bowel disease, and has been assumed to reflect long disease duration. However, we have observed that submucosal fat deposition can occur in a short period of time. MATERIALS AND METHODS: Four patients were evaluated in whom serial CT examinations showed intramural fat deposition occurring within six months of a normal study. Confirmation of fatty deposition was made by Hounsfield unit measurement in all patients and by pathologic examination of bowel specimens in two patients. RESULTS: All four patients received cytoreductive chemotherapy for treatment of lymphoma or leukemia prior to the development of fat deposition. In all patients, serial CT examination documented the occurrence of fat-attenuation bowel wall thickening that developed in a short time period (12, 36, 67, and 186 days). Three of the four cases were initially misinterpreted as wall thickening from other causes (intussusception or colitis). Pathologic examination of bowel in the two patients with the shortest time intervals confirmed the presence of mature fat confined to the submucosa. CONCLUSION: These cases demonstrate that submucosal fat deposition in bowel wall is not limited to inflammatory bowel disease and other longstanding, chronic diseases; fatty infiltration can occur in a relatively short period of time, and is particularly likely to occur after cytoreductive therapy.

Adipose Tissue↗

FDG-PET evaluation of indeterminate pancreatic masses.

PURPOSE: The purpose of this study was to assess the ability of PET with 2-[18F]fluoro-2-deoxy-D-glucose (FDG) to differentiate benign from malignant pancreatic masses in patients with indeterminate findings on CT. METHOD: We performed FDG-PET on 12 patients with indeterminate mass lesions and 2 patients with CT findings typical for malignancy. Eight were found to have pancreatic carcinoma and six had benign lesions. The final diagnosis was histopathologically confirmed in all patients but two with a presumed diagnosis of focal pancreatitis based on stable clinical follow-up for at least 12 months. Lesion uptake of FDG was evaluated qualitatively and semiquantitatively by determination of the standardized uptake value (SUV) RESULTS: With use of a 2.5 cutoff value for SUV, all eight malignant and four of six benign lesions were correctly categorized. Qualitative evaluation gave the same results. The two false-positive lesions had elevated SUV values of 3.4 and 3.8, respectively. CONCLUSION: Our results indicate that FDG-PET has potential value for assessing patients with CT findings that are indeterminate for pancreatic carcinoma. FDG-PET may obviate invasive diagnostic procedures in many patients with benign disease.

Adult↗