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Biomedical subjects

D M Blair

Publications and source records attributed to D M Blair.

At least 19 recordsLinked to original sources
PubMed1982

Cardiac emergencies.

Learning to effectively treat cardiac emergencies is not an easy task. It is my opinion that mastery of material presented herein will ensure minimal competency. Finding practical experiences to help develop the necessary medical skills will require imagination and creativity. The following are offered as possible resources:1. Attend the American Heart Association's basis and advanced life support classes. (CPR training must be repeated at six-month intervals.) 2. Spend several days and/or nights in the emergency room at a local hospital observing (helping with(emergency care. #. Spend time with a mobile coronary care unit if available in your community. 4. Watch and do venipunctures at the local blood bank or donor center. 5. Observe in the intensive care unit at a local hospital. 6. Assist an oral surgeon in preparing intravenous lines and monitor a patient during sedation. 7. Observe administration of oxygen by an anesthesiologist in the operating room at a local hospital.

Angina Pectoris↗
PubMed1981

Studies in fentanyl-supplemented anaesthesia: awareness and effect of naloxone on early post-operative recovery.

Ninety-nine unselected patients were given a standardized general anaesthetic with fentanyl 1.5 microgram . kg-1 every 30 minutes and were randomly divided into three equal groups; Group I patients received naloxone 0.1 mg. Group II naloxone 0.2 mg and Group III naloxone 0.4 mg intravenously at the end of the operation and after the reversal of neuromuscular blockade. After naloxone the level of consciousness lightened and the response to stimulus increased: the changes were significant in all three groups and the actual changes were significantly greater in Groups II and III compared with Group I. In the Recovery Room there was no significant difference among the Groups for shivering, nausea, vomiting or pain. The incidence of operative awareness was one per cent and that of dreaming eight per cent and this was unrelated to naloxone dosage. Patient acceptance was high, seven patients not wanting this type of anaesthesia again due to (a) light premedication (inherent in the study design), two patients; (b) nausea and vomiting, four patients; and (c) slow awakening, one patient.

Anesthesia↗
PubMed1977

Scanning electron microscopy of L-929 cells exposed to interferon and reovirus.

L-929 cells were studied under the scanning electron microscope (SEM) in the course of reovirus infection with and without prior interferon treatment. Two major stages in the cytopathic effect (CPE) were identified on the basis of fine surface morphology as revealed by SEM. Uninfected control cells were spindle-shaped with microvilli and numerous filopodia and were firmly attached to the substratum. In stage 1 of CPE, the cells lose filopodia and develop large blebs. Stage 2 is characterized by undulating surface and pits on the nearly spherical cells which are devoid of microvilli and filopodia. At all time intervals observed post infection, interferon-treated reovirus-infected cells showed more advanced CPE than the non-interferon-treated reovirus-infected counterpart controls.

Cytopathogenic Effect, Viral↗
PubMed1976

Dose-finding trials of oral oxamniquine in Rhodesia.

Oral oxamniquine at a total dose of 60 mg/kg (given in 4 equal doses morning and evening over 2 days, after food) is an efficient and apparently very safe drug for the treatment of Schistosoma mansoni infections. Lower doses, or shorter schedules of treatment, are less efficient. The drug has little or no effect on S. haematobium infections. Side-effects are mild and infrequent.

Adolescent↗