PubMed HealthSearch

Biomedical subjects

D M Davis

Publications and source records attributed to D M Davis.

At least 19 recordsLinked to original sources

Arthrotomy versus arthroscopy and partial synovectomy for treatment of experimentally induced infectious arthritis in horses.

To evaluate the clinical, laboratory, and histologic effects of 2 methods of treatment for infectious arthritis in horses, Staphylococcus aureus (3.4 to 3.9 x 10(3) colony-forming units) was inoculated into the tarsocrural joints of 8 horses on day 0. Each horse was treated with phenylbutazone (2 g, PO, q 24 h) and gentamicin sulfate (2.2 mg/kg of body weight, IV, q 8 h) for 14 days. On day 2, general anesthesia was induced, and each horse had 1 tarsocrural joint treated by arthrotomy, with removal of accessible fibrin and lavage with 3 L of sterile balanced electrolyte solution. An indwelling plastic drain was placed in the standing horse to provide a means for lavage with 3 L of balanced electrolyte solution twice daily for 72 hours. The contralateral tarsocrural joint was treated via arthroscopic debridement, synovectomy, and lavage with 3 L of balanced electrolyte solution. Arthrotomy and arthroscopic portals were allowed to heal by second intention. Lameness and thermographic examinations, analysis and bacteriologic culture of synovia, CBC, and WBC differential count were performed prior to inoculation and on days 1, 3, 6, 8, and 13. On day 14, each horse was euthanatized, and the joints were measured, opened, and photographed. Synovium and articular cartilage were obtained for semiquantitative histologic (H&E stain) and histochemical (safranin O fast green stain) evaluation. Lameness and joint circumference were significantly (P less than 0.05) greater in limbs treated by arthroscopy, synovectomy, and lavage. Arthrotomy with lavage eliminated the S aureus infection significantly (P less than 0.05) earlier than arthroscopy, synovectomy, and lavage, however, both treatments eliminated the infection in all but a single joint.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals

Hypoglycemia and hepatic ischemic necrosis after small intestinal incarceration through the epiploic foramen in a horse.

A 16-year-old stallion was presented to the Louisiana State University Veterinary Teaching Hospital for evaluation of acute abdominal pain. Physical examination and diagnostic procedures indicated a strangulating obstruction of the small intestine. At exploratory celiotomy, a strangulating incarceration of the jejunum through the epiploic foramen was found. The incarcerated small intestine was reduced, then resection of the nonviable bowel and anastomosis performed. After surgery, the horse exhibited clinical signs and laboratory findings associated with hypoglycemia and died in spite of emergency treatment. On post-mortem examination, a large thrombus was present in the portal vein at the level of the epiploic foramen and the liver had multiple large infarcted areas. The post-operative signs of hypoglycemia and necropsy findings of widespread hepatic ischemic necrosis are complications of epiploic foramen incarceration of the small intestine not previously reported and may in part explain the high mortality rate described for this lesion.

Abdominal Pain

Resection of a cervical tracheal bronchus in a foal.

A 3-day-old Thoroughbred foal developed a large, air-distended, midcervical swelling that was diagnosed as a congenital tracheal bronchus with associated ectopic lung tissue. Clinical signs consisted of a compressible air-filled sac that enveloped the trachea. The nature and extent of the defect were evaluated endoscopically and radiographically. Surgical resection of the bronchus and associated air-filled sac resulted in a functionally and cosmetically acceptable outcome.

Animals

Osteochondritis dissecans of the tarsocrural joint: results of treatment with arthroscopic surgery.

The technique and results of arthroscopic surgery for the treatment of osteochondritis dissecans in 318 tarsocrural joints in 225 horses are reported. Of the 225 horses, 154 were racehorses or intended for racing. Arthroscopic surgery was an effective technique for treating osteochondritis dissecans of the tarsocrural joint. The overall functional ability and cosmetic appearance of the limbs were excellent. Post surgical follow-up information was obtained for 183 horses, of which 140 (76.5 per cent) raced successfully or performed their intended use following surgery. Of the remaining 43, 11 were considered to still have a tarsocrural joint problem, 19 developed other problems precluding successful performance, eight were considered poor racehorses without any lameness problems identified, three were killed because of septic arthritis and two died from other causes. There was no significant effect of age, sex or limb involvement on the outcome. The size of the intermediate ridge lesions had no effect on prognosis but the presence of degenerative or erosive changes in the articular cartilage significantly decreased the prognosis. The synovial effusion resolved in 117/131 racehorse joints (89.3 per cent) and 64 of 86 non-racehorse joints (74.4 per cent) with follow-up. The outcome for synovial fluid resolution was significantly inferior for lesions of the lateral trochlear ridge of the talus or medial malleolus of the tibia compared to distal intermediate ridge lesions. There was no significant relationship between resolution of effusion and successful performance outcome.

Animals

Fractography of a bis-GMA resin.

The fracture behavior of a bis-GMA resin was studied by means of the double-torsion test. The fracture parameter measured was the stress-intensity factor. Fracture occurred in either a stick-slip (unstable) or continuous (stable) manner, depending upon the test conditions. When stick-slip propagation occurred, the fracture surfaces showed characteristic crack-arrest lines. The fracture surfaces were examined by use of a reflected-light optical microscope. The stress-intensity factor for crack initiation was found to be related to the size of the crack-arrest line which, in turn, could be related to the Dugdale model for plastic zone size. The evidence supported the concept that the behavior of the crack during propagation was controlled by the amount of plastic deformation occurring at the crack tip.

Bisphenol A-Glycidyl Methacrylate

Osseointegrated implants--principles and practice: 1. Osseointegration and surgical techniques with the Nobelpharma implant system.

In this series of three articles the authors describe some of the principles and practice of osseointegrated implants. Part 1 gives a detailed description of the surgical techniques required to establish osseointegrated implant fixtures (with special reference to the Branemark system). The article then gives guidance on patient selection and treatment planning. Part 2 will go on to consider prosthetic rehabilitation using osseointegrated implant fixtures. Part 3 will conclude the series by presenting a number of case studies.

Alveolar Process

Osseointegrated implants--principles and practice: 3. Case treatments with the Nobelpharma implant system.

In this series of three articles the authors describe some of the principles and practice of osseointegrated implants. Part 1 gave a detailed description of the surgical techniques to establish osseointegrated implants (with special reference to the Branemark system), guidance on patient selection and treatment planning. Part 2 described prosthetic rehabilitation using osseointegrated implant fixtures. This article concludes the series by presenting a number of case studies.

Adult

Osseointegrated implants--principles and practice: 2. Prosthetic rehabilitation with osseointegrated implants.

In this series of three articles the authors describe some of the principles and practice of osseointegrated implants. Part 1 gave a detailed description of the surgical techniques required to establish osseointegrated implant fixtures (with special reference to the Branemark system), and gave guidance on patient selection and treatment planning. Part 2 now considers prosthetic rehabilitation techniques with osseointegrated implants for complete dentures, complete overdentures, partial bridges, and single tooth replacement cases. Part 3 will conclude the series by presenting a number of case studies.

Dental Implantation, Endosseous

Immediate obturation for partial maxillectomy.

Modifications of the split maxillectomy prosthesis, secured with a transnasal wire, are recommended to ensure ease of obturation of the surgical cavity and, subsequently, rapid replacement of the original stent.

Humans

An investigation into the fracture behavior of a particulate-filled bis-GMA resin.

Dental composites are being increasingly used to restore occlusal surfaces of posterior teeth. If these restorations are not to fracture in service, an understanding of their fracture behavior is essential. The fracture parameter used is the stress-intensity factor at crack instability (KIC). This has been calculated by means of the double-torsion test in a mechanical testing machine. The fracture behavior of the composite was studied by varying: the amount of filler (7%, 15%, 26%, and 41% by volume); the surface treatment of the filler (coated or uncoated); the environment (air and water); and the cross-head rate (0.05, 0.5, 5, and 50 mm/min). Fracture was found to occur in either a continuous (stable) or stick-slip (unstable) manner. The stick-slip behavior was due to blunting of the crack tip, which was controlled by the yield behavior. When there was no significant blunting, continuous crack growth occurred. An unique relationship was found to exist between the yield stress and the stress-intensity factor for all conditions of testing.

Acrylates

Diagnostic-related groups: their impact on an inpatient rehabilitation program.

Prospective payment by diagnostic-related groups (DRGs) was expected to result in early discharges from acute care hospitals. Early transfers of patients to rehabilitation programs were anticipated, since inpatient rehabilitation programs were exempt from the prospective payment plan. A retrospective study of 516 patient records at our hospital between July 1, 1983, and June 30, 1985, was undertaken to examine changes in the major parameters of the rehabilitation program. No changes in proportions of individuals by diagnostic group, age, or gender were found. No significant change in length of stay occurred. After prospective payment took effect, the average patient admitted to rehabilitation was more impaired regardless of age, yet patients over 65 years showed comparable functional levels at discharge. More medical complications during rehabilitation stay were noted. Most patients continued to return to a home environment. Most parameters did not change after the advent of DRGs.

Aged

Weight of evidence supports one operation for "ratios" and "differences" of heaviness.

This paper investigates an apparent contradiction between recent studies of "ratios" and "differences" of heaviness. Birnbaum and Veit (1974) found a single rank order for judgments in the two tasks, whereas Rule, Curtis, and Mullin (1981), who used a different stimulus set, procedure, and experimental design, reported two orders. To investigate the cause of this discrepancy, the present study manipulated the experimental design using the same stimuli and procedure as Rule et al. (1981). In one experiment (within-subject designs), each subject judged all combinations of the standard and comparison stimulus; in the other experiment (between-subjects designs) each subject received only one standard, and different groups of subjects were given different standards. "Ratios" and "differences" of heaviness were monotonically related for the majority of subjects who judged all combinations of standards and comparisons. Variations in the modulus and response examples did not affect the rank order of "ratios" within subjects. These results suggest that the contradiction in results is due to the difference in experimental design rather than differences in stimuli or procedure. In the between-subjects designs, the rank order of the "ratio" judgments depended on the standards and examples. Both previous and present results are consistent with the theory that subjects use one operation, subtraction, for both tasks and that the judgment function varies with between-subjects manipulations of the standard, examples, and modulus.

Humans

Continuous subcutaneous infusion of morphine in children with cancer.

Seventeen children with severe pain due to malignant neoplasm were successfully treated with a subcutaneous infusion of morphine sulfate using a syringe pump. Pain relief was adequate in every case without major side effects. The median dosage required was 0.06 mg/kg/hr (range, 0.025 to 1.79 mg/kg/hr). Three patients received the subcutaneous infusion at home. No patient required an intravenous line for pain control.

Adolescent