PubMed Health⌕ Search

Biomedical subjects

D M Elston

Publications and source records attributed to D M Elston.

At least 73 records · Page 4Linked to original sources
PubMed1998

Nevoid basal cell carcinoma syndrome in a black child.

Nevoid basal cell carcinoma syndrome (NBCCS) is rare in black persons. We describe an 11-year-old black boy with NBCCS who presented with exotropia and a painful, expanding, cystic mass in the left posterior alveolar ridge. Further examination revealed odontogenic keratocysts with palmar and plantar pitting. Less than 5% of reported patients with NBCCS are black. To our knowledge, this is the first report of a black patient with NBCCS presenting with exotropia and an impacted molar displaced into the orbit by an odontogenic keratocyst.

Basal Cell Nevus Syndrome↗
PubMed1998

Lichen planus associated with hepatitis C.

The cause of lichen planus is unknown. Oral erosive lichen planus has been reported in association with liver disease. We describe a patient with chronic hepatitis C acquired through a blood transfusion with subsequent development of widespread hypertrophic lichen planus.

Hepatitis C, Chronic↗
PubMed1998

Multiple lower extremity and penile spindle cell hemangioendotheliomas.

Spindle cell hemangioendothelioma (SCH) is a rare vascular neoplasm characterized by cavernous spaces, thrombi, phleboliths, and spindle cells. The lesions may arise at sites of vascular injury. We describe a 38-year-old man with multiple subcutaneous and penile SCHs. Patients with SCH should be screened for Maffucci's syndrome.

Adult↗
PubMed1998

Topical 5-fluorouracil treatment for psoriatic trachyonychia.

Psoriatic nail involvement is common and usually accompanies other associated cutaneous or systemic lesions. The occurrence of psoriatic nail involvement has been noted in up to 50 percent of patients. There is no consistently effective therapy for psoriatic nail involvement. We report a beneficial response following a short course of topically applied 5 percent 5-fluorouracil cream.

Administration, Topical↗
PubMed1998

Palmoplantar pustulosis associated with sternocostoclavicular hyperostosis.

Palmoplantar pustulosis associated with sternocostoclavicular hyperostosis is characterized by asymmetrical and nonerosive involvement of the sternocostoclavicular joint, spine, and peripheral joints in association with palmoplantar pustulosis. This seronegative arthrosteitis has been most frequently described in the rheumatologic literature. Male and female patients are affect equally, but there tends to be a higher prevalence in Japan and Scandinavian countries. We present a case of 50-year-old man who presented with palmoplantar pustulosis that preceded his sternocostoclavicular hyperostotic symptoms by 1 to 2 years.

Diagnosis, Differential↗
PubMed1998

Elephantiasis nostras verrucosa.

Elephantiasis nostras verrucosa is a rare, chronic, deforming disorder characterized by hyperkeratosis and papillomatosis of the epidermis with underlying woody fibrosis of the dermis and subcutaneous tissue. Chronic lymphedema, either congenital or secondary to infection, surgery, radiation, neoplastic obstruction, obesity, portal hypertension, or chronic congestive heart failure, plays a pivotal role in the pathogenesis. Without appropriate intervention, the slowly progressive cutaneous changes will culminate in massive and grotesque enlargement of the affected body region. In the following case report, the natural history and the management of elephantiasis nostras are discussed.

Diagnosis, Differential↗
PubMed1998

Autoimmune bullous eruption localized to a breast reconstruction site: response to niacinamide.

A case of bullous pemphigoid responding to niacinamide as monotherapy is reported. Clinically, the patient presented with bullous lesions localized to the left breast. She had a history of a left breast mastectomy for breast cancer. This was followed by radiation therapy to the left chest wall and delayed left breast reconstruction achieved with a transposition flap of the latissimus dorsi muscle. There have been reports of bullous pemphigoid treated with a combination of tetracycline and niacinamide. This is the first report, to our knowledge, of a case of bullous pemphigoid responding to niacinamide alone.

Autoimmune Diseases↗
PubMed1998

Cutaneous ulcers of refractory adult dermatomyositis responsive to intravenous immunoglobulin.

We report the case of a woman from the Bahamas who presented with many of the classic manifestations of dermatomyositis. She responded well to initial therapy, which included oral corticosteroids, low-dosage methotrexate, and hydroxychloroquine. The cutaneous component of her disease flared dramatically months later, and progressed despite aggressive therapy with the higher dosages of the same medications. Therapy with intravenous immunoglobulin (IVIG) was initiated and the patient stopped forming new cutaneous ulcers within 1 to 2 weeks. Theories about the mechanism of action of IVIG, and practical guidelines for its use in treating patients with dermatomyositis, are briefly reviewed.

Dermatologic Agents↗
PubMed1998

Acquired perforating dermatosis in a patient with chronic renal failure and diabetes mellitus.

Perforating disorders in patients with chronic renal failure (CRF), diabetes mellitus (DM), or both, may resemble any or all of the four classic cutaneous perforating disorders. However, due to the highly variable and overlapping histologic appearance of the lesions in patients with CRF, DM, or both, it may be useful to categorized these lesions as a distinct, yet encompassing process, termed by Rapini as acquired perforating dermatosis. We describe a patient with both CRF and DM with acquired perforating dermatosis.

Diabetes Complications↗
PubMed1997

Dermatoses of the glans penis and prepuce.

A wide range of infectious, neoplastic, and inflammatory dermatoses can affect the glans penis or prepuce. Some are unique to the genitalia. Other more common dermatoses may have a unique appearance when they involve genital skin and mucosa. A thorough understanding of regional anatomy and a systematic diagnostic approach are helpful in the management of a refractory penile dermatosis. We review embryology and regional anatomy, drug-induced eruptions, allergic and irritant dermatitis, infection, neoplasia, and traumatic and inflammatory dermatoses as they relate to the glans and prepuce. Our discussion focuses on the clinical features, office laboratory studies, and histopathologic findings that assist in diagnosis and treatment.

Drug Eruptions↗