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Biomedical subjects

D M Jones

Publications and source records attributed to D M Jones.

At least 307 records · Page 17Linked to original sources

Incidence of haemagglutinating antibodies to meningococci in north-west England.

USING AN INDIRECT HAEMAGGLUTINATION TECHNIQUE THE INCIDENCE OF MENINGOCOCCAL ANTIBODIES IN ADULTS WAS FOUND TO BE: group A 21%, group B 3%, and group C 20%. The reasons for some differences between these results and those obtained in America are discussed. A low incidence of antibody was detected in preschool children but the incidence in school children was found to approach that of adults. Comparison of the antibody incidence in the adult population of an area where clinical infections were occurring with that in a similar population elsewhere failed to detect any significant difference.

Adult↗

Immunoelectroosmophoresis in the diagnosis of meningococcal infections.

Specimens of cerebrospinal fluid and serum from 22 cases of meningococcal infection were examined by immunoelectroosmophoresis and the results compared with those obtained by microscopy and culture. The results were the same except that three of 10 cases of group B infection were not diagnosed by immunoelectroosmophoresis and two of 10 cases of group C infection were not diagnosed by culture. The sensitivity of the method depends on the potency of the antiserum used and antisera from commercial sources were satisfactory except for those prepared against group B meningococci. The method may be more sensitive than microscopy and culture under certain conditions, in particular, where the patient has already begun antibiotic treatment, where the specimens have become contaminated and, where the infecting organism is either a group A or group C meningococcus.

Anti-Bacterial Agents↗

Infections of Scribner and Brescia arteriovenous shunts.

The incidence of infections of Scribner shunts and Brescia fistulae in patients receiving intermittent haemodialysis was compared. In both groups infection was most commonly due to Staphylococcus aureus and was associated especially with carriage of this organism on the skin of the limb where the shunt or fistula was sited. The incidence of local infection was much less with the Brescia fistula but this was accompanied by a relatively higher incidence of septicaemia.

Arteriovenous Shunt, Surgical↗

Dialyser gaskets.

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Bacteria↗

Bacteriological studies of the modified Kiil dialyser.

Bacterial proliferation in dialysis fluid during haemodialysis may be associated with rigors, hypotension, and bacteraemia. Investigations carried out in a period in which rigors were particularly common showed the source of bacteria to be parts of the gasket system of the Kiil dialyser, areas that are inaccessible to disinfectants.

Disinfectants↗

Antibody to Mycoplasma hominis in patients with respiratory disease.

An attempt was made to evaluate the role of Mycoplasma hominis in respiratory infection in adults. Sera collected from patients admitted to hospital with respiratory infections were examined for antibody to M. hominis. The incidence of antibody was no higher than that found previously in patients without respiratory disease.

Antibodies↗

Neonatal eye infections due to Mycoplasma hominis.

In one year Mycoplasma hominis was isolated from 8 out of 250 clinically infected eyes of newborn infants. This infection occurred in only a small proportion of babies whose mothers carried the organism in the vagina. Probably mycoplasma infection of the eye in neonates is commoner than is realized.

Adolescent↗