Biomedical subjects
D M Kozart
Publications and source records attributed to D M Kozart.
Echographic evaluation of primary cysts of the iris pigment epithelium.
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Variability and reproducibility of optic disk topographic measurements with the Rodenstock Optic Nerve Head Analyzer.
Variability of optic disk topographic measurements obtained with the Rodenstock Optic Nerve Head Analyzer was determined by obtaining three separate images on one eye of ten normal subjects and nine subjects without glaucoma. Marking of the disk margin was performed in a random and masked fashion on each image three times by three independent observers. The overall variabilities of the measurements of the subjects with glaucoma were not statistically different from those of the normal subjects. Overall variability was about 0.2 mm2 for total disk area, 0.08 for cup/disk ratio, 0.2 mm2 for disk rim area, and 0.07 mm3 for cup volume. The largest component of the variability was the result of acquisition of separate images of the optic disk at different times. Observer inconsistency in marking the disk edge was relatively small. Based on the expected amount of random variability of the measurements, we proposed criteria for detecting significant change in the optic disk over time.
Retinal circulation during a spontaneous rise of intraocular pressure.
The retinal haemodynamic changes occurring in an eye with a spontaneous elevation of intraocular pressure were investigated by bidirectional laser Doppler velocimetry and monochromatic fundus photography. At an intraocular pressure of 47 mmHg the blood velocity and volumetric blood flow rate were significantly smaller and arterial blood velocity pulsatility was significantly greater than normal. The corresponding 88% reduction in perfusion pressure was accompanied by a 67% reduction in total retinal blood flow, indicating that autoregulation is not efficient at this level of intraocular pressure. An Octopus visual field examination obtained immediately following blood flow measurements suggested that the central retina can preserve a fairly good function under a total retinal blood flow rate of about one-third of the normal value.
Argon laser trabeculoplasty in black and white patients with primary open-angle glaucoma.
The effect of argon laser trabeculoplasty (ALT) on lowering intraocular pressure (IOP) was studied retrospectively in 68 black patients and 42 white patients with uncontrolled primary open-angle glaucoma on maximally tolerated medical therapy. Patients with the diagnosis of pigmentary or pseudoexfoliation glaucoma and those having previous intraocular or laser surgery were excluded. While the mean age of the black patients (66.9 years) was lower than the white patients (72.2 years), the prelaser IOP was similar between the two groups: 26.2 mmHg for the black patients and 25.5 mmHg for the white patients. The mean IOP one year (18.4 mmHg for black patients and 18.4 mmHg for white patients) and two years (19.5 mmHg and 20.3 mmHg, respectively) after ALT was the same between the two groups of patients. A similar percentage of black (85%) and white (83%) patients showed more than a 15% decrease in IOP from their prelaser values one year after treatment. The IOP lowering effect of ALT decreased during the second post-operative year; but the diminished response was identical in patients of both races, with 71% of patients of both groups still showing greater than 15% reduction from their pre-laser IOP. We conclude that ALT is equally effective in lowering IOP for black and white patients with medically uncontrolled primary open-angle glaucoma.
Emergency management of injuries to the eye and adnexa.
In the initial evaluation of injuries to the eye and adnexa, much useful and important information can be obtained from an accurate history and a carefully performed physical examination using readily available and familiar instrumentation. The appropriate disposition of the patient with an eye injury is crucial in salvaging useful vision.
Intraocular pressure status in 100 consecutive patients with exfoliation syndrome.
An evaluation of 100 consecutive patients in whom the exfoliation syndrome was detected as an incidental finding revealed the incidence of glaucoma to be lower than previously reported. There were 75 women and 25 men in the study. Seventy-six patients had unilateral and 24 patients had bilateral involvement. The mean age of the unilateral group was 70 years and that of the bilateral group, 71 years. Of 124 eyes having the exfoliation syndrome, 78% had normal intraocular pressure, 15% had ocular hypertension (intraocular pressure greater than 22 mm Hg but no cupping or field loss), and 7% had glaucoma. Women out-numbered men in normotensive and ocular hypertensive groups, but no sex difference was apparent in the group with glaucoma. In the 76 patients in the unilateral group, 13 eyes having the exfoliation syndrome had ocular hypertension, and three had glaucoma. In five of the 16 patients with ocular pressure abnormalities in the eye with exfoliation syndrome, the fellow eye had ocular hypertension.
Stripping of Descemet's membrane after glaucoma surgery.
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Tolerated eyelash embedded in the retina.
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Light and electron microscopic study of regional morphologic differences in the processes of the ciliary body in the rabbit.
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Uses of the Sheets lens glide in contemporary cataract.
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Spontaneous cysts of the ciliary epithelium.
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