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Biomedical subjects

D M Laskin

Publications and source records attributed to D M Laskin.

At least 253 records · Page 14Linked to original sources

Experimental osteogenesis with demineralized allogeneic bone matrix in extraskeletal sites.

Male albino rats were used to study the osteogenic potential of demineralized allogeneic bone matrix (DABM) grafts, in different stages of demineralization, placed in the anterior abdominal wall. The clinical evaluation, radiologic examination, calcium determination, and histologic (light and electron microscopic) studies showed that completely demineralized allogeneic bone matrix (CDABM) grafts were not rejected and that they stimulated new bone formation at the transplant sites. On the other hand, partially demineralized allogeneic bone matrix (PDABM) grafts were frequently rejected and showed minimal bone induction and gradual demineralization.

Abdominal Muscles↗

The effects of immobilization on the primate temporomandibular joint: a histologic and histochemical study.

The effects of prolonged immobilization on the primate temporomandibular joint (TMJ) condylar cartilage are reported. After eight weeks of immobilization, changes were assayed histochemically using the specific glycosaminoglycan (GAG) stain safranin O. Following the immobilization period, the articulating cartilage showed marked thinning, disorganization, and loss of the superficial GAG stain. After two weeks of remobilization, further thinning had occurred and GAG staining was nearly absent. Sections from condyles of animals sacrificed serially from two weeks to eight months after immobilization showed a gradual return to the thickness and GAG content of the control animals' condyles. But even at this stage, GAG staining was less marked than in the controls, and zonal reorganization was incomplete. These results suggest that TMJ immobilization is not wholly benign procedure.

Animals↗

Psychological factors in the etiology, progression, and treatment of MPD syndrome.

The evidence is abundant and clear: psychological factors do have an important role in the etiology, progression, and treatment of MPD syndrome. These findings have implications for therapists who wish to understand the disorder and to manage patients appropriately. In regard to etiology, they should appreciate the impact of psychological traits and states on the development of symptoms of MPD syndrome, but they should not waste time and energy in measuring or analyzing specific psychological factors in individual patients. In regard to perpetuation of the disorder, they should understand that some patients will not respond to conventional treatment despite the best efforts of any competent therapist. Finally, in regard to treatment, they should recognize the importance of nonspecific factors such as placebo effects, doctor-patient interactions, and spontaneous recoveries in the treatment response. This awareness will enhance their effectiveness as therapists and will help them to avoid using excessive or radical treatment methods.

Anxiety↗

Masticatory muscle silent periods in patients with MPD syndrome before and after treatment.

Masticatory muscle silent periods were compared in normal subjects and in patients with MPD syndrome before and after a variety of psychological, physiological, and pharmacological forms of therapy. All patients initially showed prolonged silent periods in one or more of the muscles. There was a direct relationship between prolongation and severity of symptoms. The temporalis (90.9%) and masseter (54.5%) were most frequently involved. In almost all instances the silent periods returned to the normal range following treatment.

Adult↗

Replantation of a mandibular molar: report of case.

A patient with an alveolar abscess, swelling, pain, and an extremely mobile tooth had had previous root canal treatment. Extraction was recommended but, with informed consent and the patient's desire to keep his tooth, intentional replantation was performed as a last resort. Matsura's method of canal preparation, which results in a large area of amalgam on the root surface, was used. This method did not impair healing. According to Bjorvatn and Massler, 11 application of 1% SNF2 to the root surfaces for five minutes reduces root resorption. This technique was not used in this case. Clinical and radiographic observation for almost four years substantiate this as a successful case.

Adult↗

Let's face it.

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Esthetics, Dental↗