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Biomedical subjects

D M Laskin

Publications and source records attributed to D M Laskin.

At least 91 records · Page 5Linked to original sources

Autologous pericranial graft resurfacing after high condylectomy and discectomy of the temporomandibular joint in rabbits.

PURPOSE: This study tested the effects of an autologous pericranial graft placed over the condyle on healing after high condylectomy and discectomy. MATERIALS AND METHODS: Sixteen young adult New Zealand white rabbits were divided into four test groups and a control group. Three animals from the test group and one control animal were killed at 2, 4, 8, and 12 weeks postoperatively. Each experimental animal received a high condylotomy and discectomy bilaterally. In addition, on one side a pericranial graft was placed on the shaved bone and immobilized with a tissue adhesive. RESULTS: The results showed better healing of the articular defects in the joints where grafts had been placed, including earlier and more complete soft tissue covering, more substantial neochondrogenesis, and better organization of the regenerated articular cartilage. CONCLUSION: Pericranial grafts may be helpful in facilitating healing after high condylectomy. However, technical improvements in the method of tissue fixation may be necessary.

Animals↗

Women in oral and maxillofacial surgery: factors affecting career choices, attitudes, and practice characteristics.

PURPOSE: This study analyzed the factors that attract women to the field of oral and maxillofacial surgery, their attitudes toward various aspects of the specialty, current practice patterns, and biases that may have been or are still being encountered. METHODS: Surveys were mailed to practicing female oral and maxillofacial surgeons, to oral and maxillofacial surgery residency programs to be distributed to their female residents, and to male and female dental students. RESULTS: A total of 107 surveys were sent to practicing female surgeons and 105 to oral and maxillofacial surgery programs. There was a return rate of 71% and 70%, respectively. Practicing female oral and maxillofacial surgeons tended to be young, Caucasian, and married. Fifty-nine percent were boarded, and 47% owned their own practices. Four of 76 had interrupted their residencies, and 18 had interrupted their practices at some point. More than 64% of practicing female oral and maxillofacial surgeons believed that there was a bias against women in this field. Female residents showed an overwhelming satisfaction with their career choice, but nearly half of them alluded to the need for dedication, a restriction of social life, or a concern for entering an male-dominated field. For students, the time commitment during residency and while in practice, and compromised family and social life, were the most commonly mentioned deterrents to entering oral and maxillofacial surgery, and lifestyle and the excitement of the field were its major attractions. CONCLUSION: Despite some biases in the field, women are practicing oral and maxillofacial surgery full time and are combining their career with full family lives. Among dental students, the time commitment and social compromise are the largest deterrents to entering the specialty of oral and maxillofacial surgery.

Adult↗

The effect of polytetrafluoroethylene cylinders on osteogenesis in rat fibular defects: a preliminary study.

PURPOSE: This study was designed to evaluate the use of a hollow polytetrafluorethylene stent on the healing of continuity defects in the rat fibula. MATERIALS AND METHODS: Twenty-one animals were divided into four groups. Group 1 (n = 10) had an 8-mm segment of bone and periosteum removed with no interpositional stent. Group 2 (n = 10) had bone removed, but the periosteum was maintained and no stent was placed. Group 3 (n = 11) had bone and periosteum removed and placement of a stent. Group 4 (n = 10) had only bone removed and placement of a stent. The animals were sacrificed after 12 weeks and the defects were evaluated clinically and radiographically. RESULTS: Radiographic analysis showed that nine of 10 fracture gaps in group 1 failed to heal. In group 2, seven of 10 gaps did not heal; three showed partial calcification. In group 3, four of 11 gaps were nonhealed, five showed partial calcification, and two showed complete calcification. In group 4, only two of 10 gaps failed to heal, seven showed partial calcification, and one was completely calcified. Clinical evaluation showed a similar trend. CONCLUSION: These findings suggest that guided tissue regeneration could potentially be used to bridge continuity defects without the need for a graft.

Animals↗