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D M Manning

Publications and source records attributed to D M Manning.

8 recordsLinked to original sources

Miscuffing: inappropriate blood pressure cuff application.

For the accurate indirect measurement of blood pressure (BP), the American Heart Association (AHA) now recommends that cuff size should be based solely on limb circumference. We studied prevailing cuffing habits and compared them with newly revised AHA guidelines. Monitoring our staff's cuff applications, we found that "miscuffing" occurred in 65 (32%) of 200 BP determinations on 167 unselected adult outpatients, including 61 (72%) of 85 readings taken on "nonstandard" size arms. Undercuffing large arms was the most frequent error, accounting for 84% of the miscuffings. Considering that miscuffing distorts BP readings by an average of 8.5 mm Hg systolic and 4.6 mm Hg diastolic, we can improve the accuracy of our BP determinations by remarking our cuffs and using the new AHA guidelines.

American Heart Association

Herpes zoster after splenectomy. A study of patients without malignancy.

Follow-up information was obtained on 102 unselected patients who had undergone splenectomy for nonmalignant disease (ie, trauma, surgical complications, and hematologic indications). In 422 postsplenectomy years, three cases of herpes zoster were observed, two of which were associated with generalized cutaneous dissemination. This incidence is no greater than that reported elsewhere for age-matched normal population. We conclude that in patients without malignancy, splenectomy does not predispose to herpes zoster, but may play a role in cutaneous dissemination.

Adult

Early detection of busulfan lung: report of a case.

A patient with chronic myelogenous leukemia, treated for two years with busulfan, presented with increasing dyspnea of several months' duration. Despite a normal chest radiograph, there was a markedly reduced carbon monoxide (CO) diffusing capacity (41% of predicted normal) and a restrictive ventilatory pattern on pulmonary function testing. Gallium-67 scanning revealed diffuse uptake in both lungs. The busulfan was discontinued and therapy was changed to hydroxyurea. Three months later the patient was without symptoms, the CO diffusing capacity had risen to 64% (of predicted), and the Ga-67 scan had returned to normal. The chest radiograph remained normal. Despite the lack of biopsy proof, we believe Ga-67 scanning was an aid in the early detection of cytotoxic-induced lung disease in a reversible stage. Gallium-67 scanning may be useful in the early deagnosis of pulmonary injury from cytotoxic agents.

Busulfan