Some observations on the toxicity of hexachlorophane for sheep.
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Biomedical subjects
Publications and source records attributed to D M Pugh.
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The pre-implantation embryo of the mouse undergoes a histochemically detectable change in the properties of its trophoblastic cell-surface coat in the immediate pre-implantation period. This change is oestrogen-dependent in vivo and can be induced in vitro in a concentration-dependent manner by oestradiol-17 beta. There is evidence that this coat change is of functional importance in the process of implantation, and its demonstration is of potential value as the basis of an in vitro assay of oestrogenicity.
In dogs, the mean plasma vitamin C concentration was found to be 0.88 mg/100 ml plasma while the mean buffy coat concentration of simultaneous blood aliquots was 42.98 mg/10(8) cells. A significant day-to-day variation was recorded for both parameters.