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Biomedical subjects

D M Salisbury

Publications and source records attributed to D M Salisbury.

7 recordsLinked to original sources
PubMed1979

Clinical events relating to intraventricular haemorrhage in the newborn.

Continuous measurements of arterial pressures, heart rates, respiratory movements, and respiratory rates were made from birth in 44 infants at risk from intraventricular haemorrhage (IVH). 17 babies died with IVH, in 10 of whom the event was timed objectively. Events in these babies were compared with survivors of similar birthweights, gestational ages, severity of birth asphyxia, and severity of hyaline membrane disease (HMD). IVH followed severe HMD and was associated with cessation of the babies' own respiratory efforts while on a ventilator and also with characteristic cardiorespiratory events. The minimum arterial pressure before IVH was lower than in comparable babies who survived. It is suggested that fluctuations of systemic blood pressure from initial low levels may be important in the pathogenesis of IVH. It is possible that changes in cerebral blood flow are of even greater significance.

Asphyxia Neonatorum↗
PubMed1978

Peripheral pulmonary artery stenosis.

A term infant, born by caesarean section for fetal distress, developed grunting and cyanosis by 15 minutes of age. Ventilation at low pressures was achieved without difficulty but did not improve blood gas levels, and he died at 26 hours. Necropsy examination showed large heart and small lungs; histologically the lungs showed multiple obstructive lesions at medium size pulmonary artery level.

Constriction, Pathologic↗
PubMed1977

Paediatric preparation for multiple premature births.

We describe the managment of 2 sets of pre-term quadruplets born to 2 women pregnant concurrently following the induction of ovulation with gonadotrophin. Careful antenatal planning was necessary to provide for each of the 8 pre-term infants a standard of neonatal medical and nursing care comparable to that normally available for singleton pre-term infants.

Adult↗
PubMed1977

Effect of blood transfusion in low birthweight infants.

143 fresh blood transfusions were given to 32 low birthweight babies, 28 of whom had hyaline membrane disease. The arterial or central venous pressure was raised by a blood transfusion if before transfusion the mean arterial pressure was less than 35 mmHg or if the diastolic central venous pressure was less than -- 0-5 mmHg. There was no effect of blood transfusion on pH. It therefore appears either that metabolic acidosis in hyaline membrane disease is not caused by poor peripheral perfusion or that blood transfusion does not increase peripheral blood flow in this condition. The safety of the procedure is assessed.

Blood↗
PubMed1975

Bottle-feeding: influence of teat-hole on suck volume.

Infants have been fed with teats whose end-holes varied in shape and size. Two types of feeding-bottles were used. With conventional feeding-bottles, variations of teat-hole shape and size did not significantly alter the volumes of milk obtained at each suck. However, when an infant feeding-bottle was used which contained a valve, then variations in teat-hole shape and size did alter the volumes of milk obtained. The volume of milk obtained from a standard teat under such circumstances was the same as the volume previously calculated for breast-feeding.

Animals↗
PubMed1975

Breathing and sucking during feeding in the newborn.

Eighteen normal full-time infants aged from 1-10 days were fed both normal saline and distilled water from a conventional feeding bottle. Fifty-four sets of observations were made when 44 infants were fed both cow's milk (Half Cream Cow & Gate) and expressed human milk. During feeding, measurements were made of breathing, sucking, and the flow of milk from a feeding bottle which incorporated an electromagnetic flowmeter transducer. Integration of the flow of milk measured the volume of milk swallowed by the baby. The results suggest that the patterns of feeding and breathing differ in some infants when different fluids are given to them.

Age Factors↗