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Biomedical subjects

D M Sanders

Publications and source records attributed to D M Sanders.

10 recordsLinked to original sources
PubMed1989

Tuberculosis presenting as corticosteroid responsive wheezing in infancy.

A nine-month-old child received intermittent oral prednisolone over a 6 month period because of persistent wheezing. This therapy had appeared to improve his symptoms. At 15 months of age, a chest X-ray and culture of tracheal aspirate revealed disseminated pulmonary tuberculosis. Response to antituberculous therapy was slow, and withdrawal of steroids produced marked worsening of wheeze and respiratory distress. Corticosteroids are recognised adjuncts in the management of bronchial-lymph node tuberculosis. Responsiveness of wheezing to prednisolone does not imply that its cause is hyperreactive airways disease, and other causes should be sought particularly in developing countries.

Asthma↗
PubMed1986

Light regulation of a SSRubisco-nos chimaeric gene: photoregulatory control sequences from a C3 plant function in cells of a CAM plant.

A SSRubisco-nos chimaeric gene has been constructed, in an oncogenic Ti-plasmid vector. A 900bp soybean SSRubisco upstream fragment, carrying CAAT and TATA boxes and transcription initiation point, was fused to the nos coding region, the fusion site being within the 5'-untranslated region. When this chimaeric construct was transferred to Kalanchoe cells, nos expression was shown to be light-regulated. Thus DNA sequences responsible for light-dark control of gene expression are wholly or partly contained within the 900bp soybean SSRubisco upstream region. Moreover, this is the first demonstration that photoregulatory elements in a gene derived from a C3 plant, function in cells of a plant exhibiting the CAM trait.

Base Sequence↗
PubMed1978

Body image stereotypes: a developmental comparison.

The purpose of this study was to test the hypothesis that temperament judgments associated with different body types were dependent upon sex and age of the respondents. A total of 500 participants, 249 females and 251 males ranging from 6 to 60 years of age, were sampled. Participants were drawn from various civic, educational, institutional, and residential groups in a Southern cosmopolitan city. A paper-pencil instrument consisted of three body silhouettes (representing an ectomorph, mesomorph, and endomorph) and 40 temperament/behavior descriptors. The respondents matched each descriptor with one of the three body types. The results indicated that the descriptors were differentially associated with body types according to age groups but not by sex. The mesomorph was overwhelmingly and consistently viewed as the most positive of the three body types, but was rated somewhat more negatively as the age of the group increased. Participants of ages 6 through 25 rated the endomorph more negatively than the ectomorph, while those of ages 26-40 rates them equally. In contrast, participants over 40 years of age viewed the ectomorph more negatively than the endomorph.

Adolescent↗