Biomedical subjects
Publications and source records attributed to D M Skinker.
Renal involvement is common in Henoch-Schoenlein purpura (HSP) and, while ureteral obstruction has been described in patients with the disease, it is rare. We report a female with HSP who developed bilateral ureteral obstruction from peri-ureteral vasculitis and subsequent ureteral ischemia. Hydronephrosis and typical findings on contrast urography indicated the diagnosis.
The examination of azoospermic semen poses a special problem for the forensic scientist. Both serologic and RFLP methods may result in inconclusive results. PCR analysis is known to have an advantage in the evaluation of variably degraded, small quantities of DNA. This investigation addresses the feasibility of detecting the DNA profiles of azoospermic males in cases of suspected rape by the use of PCR amplification of the VNTR locus DIS80. DNA profiles were produced from aspermic semen samples from six vasectomized males. Two mixed postcoital vaginal samples containing azoospermic semen from two of the vasectomized males were also obtained and both revealed the combined profiles of the azoospermic semen donors and the vaginal epithelial donors. All cases resulted in an allelic banding pattern of the donor semen matching the respective blood/saliva standard.
Multiple self-inflicted gunshot wounds of the head are uncommon. Detailed history, scene investigation, autopsy findings, consideration of ballistics, and evidentiary proceedings are necessary to determine the manner of death in these cases. This report involves a pattern of atypical, self-inflicted bullet wounds of the head of a 26-year-old male. Investigation confirmed that a single eyewitness and several earwitnesses reported a single discharge of a firearm. The eyewitness testified that the decedent singly discharged a Smith & Wesson revolver, caliber .38 Special, to the right side of his head after interposing several objects between the muzzle and his skin immediately prior to discharge. He was declared brain dead two days later. At necropsy two contiguous atypical entry wounds were present in the right preauricular temple. The inferior wound was interpreted to be a near contact wound. The gray metal slug fragmented, creating separate tracks to the right maxillary sinus and the mid left posterior cerebrum, respectively. The larger, atypical wound of entry was associated with passage of the projectile through the right temporalis muscle and squamous temporal bone. The projectile, consisting of a slightly distorted empty metallic cartridge case containing a "live" primer, was recovered from its point of final lodgment in the right temporal lobe. The literature addressing paired entry wounds following single discharge of the firearm with interposed targets is relatively sparse. Cases reporting multiple bullet wounds involving suicide are only sporadically reported. This report summarizes the investigative findings supporting the determination of the manner of death and revealing the interesting origin of the "misplaced" casing.