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Biomedical subjects

D M Steven

Publications and source records attributed to D M Steven.

4 recordsLinked to original sources
PubMed1984

Carcinoma of the colon and rectum in patients under 30 years of age.

A 15-year study of large-bowel carcinoma at Groote Schuur Hospital revealed 47 patients who presented at the age of 29 years or younger. Only 1% of the White patients with large-bowel carcinoma were in this age group (similar to other Western series), whereas a much higher incidence was seen in Coloured patients (9%). We found a large number of young Coloured patients with high-grade tumours and lymph node invasion. In spite of surgery, chemotherapy and radiotherapy the prognosis for this group in particular remains extremely poor.

Adolescent↗
PubMed1984

Abdominoperineal resection of the rectum for carcinoma at Groote Schuur Hospital, Cape Town, 1971-1982.

Abdominoperineal excision of the rectum remains the accepted treatment for the majority of lower rectal adenocarcinomas. Despite advances in surgery and anaesthesia, survival has not improved over the last 40 years. Over a 12-year period the overall 5-year survival rate for patients undergoing abdominoperineal excision for adenocarcinoma of the rectum at Groote Schuur Hospital, Cape Town, was 39%. The incidence of complications associated with the operation remains high (36%). The major causes of morbidity still originate in the urinary tract and the perineal wound. Further techniques which may improve the overall survival are briefly reviewed.

Adenocarcinoma↗